HCSGD entry for IRX1
1. General information
| Official gene symbol | IRX1 |
|---|---|
| Entrez ID | 79192 |
| Gene full name | iroquois homeobox 1 |
| Other gene symbols | IRX-5 IRXA1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0072086 | Specification of loop of Henle identity | IEA | biological_process |
| GO:0072272 | Proximal/distal pattern formation involved in metanephric nephron development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3467225181 | 0.5225312830 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0532333207 |
| GSE13712_SHEAR | Down | -0.0061574271 |
| GSE13712_STATIC | Down | -0.0375777689 |
| GSE19018 | Up | 0.1774410289 |
| GSE19899_A1 | Down | -0.1607031705 |
| GSE19899_A2 | Up | 0.2438901169 |
| PubMed_21979375_A1 | Up | 0.1169091762 |
| PubMed_21979375_A2 | Down | -0.2043999267 |
| GSE35957 | Down | -0.5023316931 |
| GSE36640 | Down | -0.0223153524 |
| GSE54402 | Down | -0.0192154795 |
| GSE9593 | Down | -0.0312423533 |
| GSE43922 | Up | 0.2662987539 |
| GSE24585 | Up | 0.0729167204 |
| GSE37065 | Up | 0.1508605815 |
| GSE28863_A1 | Up | 0.0273035709 |
| GSE28863_A2 | Up | 0.1417868315 |
| GSE28863_A3 | Up | 0.2973546979 |
| GSE28863_A4 | Down | -0.1684531254 |
| GSE48662 | Up | 0.2513172299 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
