HCSGD entry for BAG6
1. General information
| Official gene symbol | BAG6 |
|---|---|
| Entrez ID | 7917 |
| Gene full name | BCL2-associated athanogene 6 |
| Other gene symbols | BAG-6 BAT3 D6S52E G3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001822 | Kidney development | IEA ISS | biological_process |
| GO:0002376 | Immune system process | IEA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0006511 | Ubiquitin-dependent protein catabolic process | IEA ISS | biological_process |
| GO:0006810 | Transport | IEA | biological_process |
| GO:0007130 | Synaptonemal complex assembly | IEA ISS | biological_process |
| GO:0007283 | Spermatogenesis | IEA ISS | biological_process |
| GO:0007420 | Brain development | IEA ISS | biological_process |
| GO:0009790 | Embryo development | IEA ISS | biological_process |
| GO:0016568 | Chromatin modification | IEA | biological_process |
| GO:0018393 | Internal peptidyl-lysine acetylation | IDA | biological_process |
| GO:0030154 | Cell differentiation | IEA | biological_process |
| GO:0030324 | Lung development | IEA ISS | biological_process |
| GO:0030544 | Hsp70 protein binding | IEA | molecular_function |
| GO:0031593 | Polyubiquitin binding | IEA ISS | molecular_function |
| GO:0032435 | Negative regulation of proteasomal ubiquitin-dependent protein catabolic process | IEA ISS | biological_process |
| GO:0042127 | Regulation of cell proliferation | IEA | biological_process |
| GO:0042771 | Intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | IMP | biological_process |
| GO:0043022 | Ribosome binding | IDA | molecular_function |
| GO:0045861 | Negative regulation of proteolysis | ISS | biological_process |
| GO:0050821 | Protein stabilization | IEA ISS | biological_process |
| GO:0070059 | Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | IEA ISS | biological_process |
| GO:0070628 | Proteasome binding | IEA ISS | molecular_function |
| GO:0071816 | Tail-anchored membrane protein insertion into ER membrane | IDA | biological_process |
| GO:0071818 | BAT3 complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1221743627 | 0.6156390335 | 0.7147702601 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1640814227 |
| GSE13712_SHEAR | Down | -0.2262389661 |
| GSE13712_STATIC | Down | -0.2597940957 |
| GSE19018 | Up | 0.3417953736 |
| GSE19899_A1 | Up | 0.0091572344 |
| GSE19899_A2 | Up | 0.1299973138 |
| PubMed_21979375_A1 | Up | 0.2848347830 |
| PubMed_21979375_A2 | Up | 1.2715498736 |
| GSE35957 | Down | -0.3061469014 |
| GSE36640 | Down | -0.2293742833 |
| GSE54402 | Up | 0.3201300364 |
| GSE9593 | Down | -0.1957361096 |
| GSE43922 | Up | 0.0122955395 |
| GSE24585 | Up | 0.1095114338 |
| GSE37065 | Down | -0.1594262965 |
| GSE28863_A1 | Up | 0.4496552312 |
| GSE28863_A2 | Up | 0.8949668348 |
| GSE28863_A3 | Up | 0.2591310226 |
| GSE28863_A4 | Down | -0.3339359749 |
| GSE48662 | Down | -0.2216139143 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025262 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031479 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1226-3p | MIMAT0005577 | MIRT036531 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-760 | MIMAT0004957 | MIRT036783 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037504 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039860 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040645 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041258 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041655 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043466 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-378a-5p | MIMAT0000731 | MIRT043997 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046630 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049283 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT051911 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
