HCSGD entry for CARD14

1. General information

Official gene symbolCARD14
Entrez ID79092
Gene full namecaspase recruitment domain family, member 14
Other gene symbolsBIMP2 CARMA2 PRP PSORS2 PSS1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001934Positive regulation of protein phosphorylationIDAbiological_process
GO:0005622IntracellularIEAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005886Plasma membraneNAScellular_component
GO:0006915Apoptotic processIEAbiological_process
GO:0007250Activation of NF-kappaB-inducing kinase activityNASbiological_process
GO:0016235AggresomeIDAcellular_component
GO:0033209Tumor necrosis factor-mediated signaling pathwayIMPbiological_process
GO:0042981Regulation of apoptotic processIEAbiological_process
GO:0043066Negative regulation of apoptotic processIMPbiological_process
GO:0050700CARD domain bindingIPImolecular_function
GO:0051092Positive regulation of NF-kappaB transcription factor activityIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.78654957640.88506394510.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0192106129
GSE13712_SHEARUp0.0007997776
GSE13712_STATICDown-0.0132420468
GSE19018Up0.0164840889
GSE19899_A1Up0.0488762239
GSE19899_A2Up0.1249341581
PubMed_21979375_A1Down-0.1336465218
PubMed_21979375_A2Down-0.0725726312
GSE35957Up0.0201908335
GSE36640Up0.0408952424
GSE54402Down-0.0466023498
GSE9593Down-0.0334079792
GSE43922Up0.0647880686
GSE24585Up0.1212507190
GSE37065Down-0.0660344267
GSE28863_A1Down-0.0872541462
GSE28863_A2Down-0.0778134932
GSE28863_A3Up0.2221102688
GSE28863_A4Up0.0903537619
GSE48662Up0.1184872262

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT022735MicroarrayFunctional MTI (Weak)18668037
hsa-miR-26b-5pMIMAT0000083MIRT029698MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.