HCSGD entry for ELOVL6
1. General information
| Official gene symbol | ELOVL6 |
|---|---|
| Entrez ID | 79071 |
| Gene full name | ELOVL fatty acid elongase 6 |
| Other gene symbols | FACE FAE LCE |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016747 | Transferase activity, transferring acyl groups other than amino-acyl groups | IEA | molecular_function |
| GO:0019367 | Fatty acid elongation, saturated fatty acid | IDA | biological_process |
| GO:0019432 | Triglyceride biosynthetic process | TAS | biological_process |
| GO:0030176 | Integral component of endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0030497 | Fatty acid elongation | IEA | biological_process |
| GO:0035338 | Long-chain fatty-acyl-CoA biosynthetic process | TAS | biological_process |
| GO:0042759 | Long-chain fatty acid biosynthetic process | IDA | biological_process |
| GO:0044255 | Cellular lipid metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7517287983 | 0.0670151324 | 0.9999902473 | 0.4884114895 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.6088596419 |
| GSE13712_SHEAR | Down | -0.3637549753 |
| GSE13712_STATIC | Down | -0.0431580844 |
| GSE19018 | Down | -0.1356199265 |
| GSE19899_A1 | Up | 0.0066254029 |
| GSE19899_A2 | Down | -0.0322692958 |
| PubMed_21979375_A1 | Down | -0.6677297885 |
| PubMed_21979375_A2 | Down | -0.0573954974 |
| GSE35957 | Down | -0.2718468421 |
| GSE36640 | Up | 0.1826158210 |
| GSE54402 | Up | 0.5719878847 |
| GSE9593 | Down | -0.0387308188 |
| GSE43922 | Down | -0.1040153123 |
| GSE24585 | Down | -0.3362288015 |
| GSE37065 | Up | 0.0132006912 |
| GSE28863_A1 | Down | -0.5899958722 |
| GSE28863_A2 | Up | 0.0574369003 |
| GSE28863_A3 | Down | -0.2949053831 |
| GSE28863_A4 | Down | -0.0414935636 |
| GSE48662 | Down | -0.5694225222 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-211-5p | MIMAT0000268 | MIRT006463 | Immunofluorescence//Microarray//qRT-PCR//Western blot | Functional MTI | 22523078 |
| hsa-miR-204-5p | MIMAT0000265 | MIRT006461 | Immunofluorescence//Microarray//qRT-PCR//Western blot | Functional MTI | 22523078 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT017106 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039875 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-106b-5p | MIMAT0000680 | MIRT044292 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049041 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-26a-5p | MIMAT0000082 | MIRT050112 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
