HCSGD entry for DDX54
1. General information
| Official gene symbol | DDX54 |
|---|---|
| Entrez ID | 79039 |
| Gene full name | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| Other gene symbols | DP97 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0003714 | Transcription corepressor activity | IDA | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0004004 | ATP-dependent RNA helicase activity | IDA | molecular_function |
| GO:0005102 | Receptor binding | IDA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA IEA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006200 | ATP catabolic process | IDA | biological_process |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0006396 | RNA processing | IDA | biological_process |
| GO:0008026 | ATP-dependent helicase activity | IEA | molecular_function |
| GO:0016070 | RNA metabolic process | IDA | biological_process |
| GO:0016818 | Hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | IEA | molecular_function |
| GO:0030331 | Estrogen receptor binding | IDA | molecular_function |
| GO:0030520 | Intracellular estrogen receptor signaling pathway | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7417595380 | 0.2665635652 | 0.9999902473 | 0.9888368132 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0724534491 |
| GSE13712_SHEAR | Down | -0.2255011330 |
| GSE13712_STATIC | Up | 0.0908508609 |
| GSE19018 | Up | 0.2009451736 |
| GSE19899_A1 | Down | -0.2525796618 |
| GSE19899_A2 | Up | 0.2484068277 |
| PubMed_21979375_A1 | Up | 0.3567787390 |
| PubMed_21979375_A2 | Down | -0.0847817035 |
| GSE35957 | Down | -0.3312604741 |
| GSE36640 | Down | -0.4701341588 |
| GSE54402 | Up | 0.0632479024 |
| GSE9593 | Down | -0.0999724250 |
| GSE43922 | Up | 0.0089750005 |
| GSE24585 | Down | -0.5391847900 |
| GSE37065 | Down | -0.2511547122 |
| GSE28863_A1 | Up | 0.0387013542 |
| GSE28863_A2 | Up | 0.1885931299 |
| GSE28863_A3 | Up | 0.0746238267 |
| GSE28863_A4 | Up | 0.0968001430 |
| GSE48662 | Up | 0.2265699142 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-192-5p | MIMAT0000222 | MIRT026599 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031772 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037544 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-5p | MIMAT0004748 | MIRT038067 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT042275 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047683 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
