HCSGD entry for ST8SIA4
1. General information
| Official gene symbol | ST8SIA4 |
|---|---|
| Entrez ID | 7903 |
| Gene full name | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 |
| Other gene symbols | PST PST1 SIAT8D ST8SIA-IV |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | TAS | cellular_component |
| GO:0001574 | Ganglioside biosynthetic process | IDA | biological_process |
| GO:0003828 | Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity | IDA | molecular_function |
| GO:0006464 | Cellular protein modification process | TAS | biological_process |
| GO:0006486 | Protein glycosylation | IDA | biological_process |
| GO:0006491 | N-glycan processing | IDA | biological_process |
| GO:0007399 | Nervous system development | TAS | biological_process |
| GO:0007411 | Axon guidance | TAS | biological_process |
| GO:0009311 | Oligosaccharide metabolic process | IDA | biological_process |
| GO:0030173 | Integral component of Golgi membrane | IEA | cellular_component |
| GO:0033691 | Sialic acid binding | IC | molecular_function |
| GO:0097503 | Sialylation | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2126692603 | 0.1764294138 | 0.8890831639 | 0.8129899510 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1343143486 |
| GSE13712_SHEAR | Down | -0.1271529292 |
| GSE13712_STATIC | Down | -0.8249645789 |
| GSE19018 | Down | -0.1958803228 |
| GSE19899_A1 | Up | 0.0891134686 |
| GSE19899_A2 | Up | 0.0142076826 |
| PubMed_21979375_A1 | Down | -0.0579420489 |
| PubMed_21979375_A2 | Up | 0.0817930713 |
| GSE35957 | Down | -0.1860345804 |
| GSE36640 | Down | -0.0481225864 |
| GSE54402 | Up | 1.7916353080 |
| GSE9593 | Down | -0.6552315404 |
| GSE43922 | Up | 0.0191952488 |
| GSE24585 | Up | 1.6924564506 |
| GSE37065 | Down | -0.2477575275 |
| GSE28863_A1 | Down | -0.2293945168 |
| GSE28863_A2 | Down | -0.1673877562 |
| GSE28863_A3 | Up | 0.0311597830 |
| GSE28863_A4 | Down | -0.0232918734 |
| GSE48662 | Down | -0.0436519564 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017872 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 12773392 | In addition, Clr6 interacts with homologs of the mammalian transcriptional co-repressors Sin3, Pst1 and Pst2, and a WD40 repeat-containing protein, Prw1 |
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