HCSGD entry for GGCT
1. General information
| Official gene symbol | GGCT |
|---|---|
| Entrez ID | 79017 |
| Gene full name | gamma-glutamylcyclotransferase |
| Other gene symbols | C7orf24 CRF21 GCTG GGC |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001836 | Release of cytochrome c from mitochondria | IMP | biological_process |
| GO:0003839 | Gamma-glutamylcyclotransferase activity | IDA IEA TAS | molecular_function |
| GO:0005829 | Cytosol | IDA TAS | cellular_component |
| GO:0006750 | Glutathione biosynthetic process | IEA TAS | biological_process |
| GO:0006805 | Xenobiotic metabolic process | TAS | biological_process |
| GO:0042803 | Protein homodimerization activity | IDA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:1901687 | Glutathione derivative biosynthetic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3715108962 | 0.0637963945 | 0.9999902473 | 0.4762294101 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1512906637 |
| GSE13712_SHEAR | Down | -0.2804741349 |
| GSE13712_STATIC | Up | 0.0133424992 |
| GSE19018 | Down | -1.3131697508 |
| GSE19899_A1 | Up | 0.5466944022 |
| GSE19899_A2 | Down | -0.0039967858 |
| PubMed_21979375_A1 | Up | 0.5012813760 |
| PubMed_21979375_A2 | Up | 0.0300695874 |
| GSE35957 | Down | -0.7485052061 |
| GSE36640 | Down | -0.7573673662 |
| GSE54402 | Up | 0.3785836269 |
| GSE9593 | Down | -0.6993188179 |
| GSE43922 | Up | 0.3696240554 |
| GSE24585 | Down | -0.4076470488 |
| GSE37065 | Down | -0.4125881905 |
| GSE28863_A1 | Up | 0.1144645830 |
| GSE28863_A2 | Up | 0.5413438768 |
| GSE28863_A3 | Down | -0.3544237284 |
| GSE28863_A4 | Down | -0.0782653365 |
| GSE48662 | Down | -0.0793278904 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7b-5p | MIMAT0000063 | MIRT005232 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028630 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-340-3p | MIMAT0000750 | MIRT043851 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125a-5p | MIMAT0000443 | MIRT045750 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
