HCSGD entry for DDX50
1. General information
| Official gene symbol | DDX50 |
|---|---|
| Entrez ID | 79009 |
| Gene full name | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 |
| Other gene symbols | GU2 GUB RH-II/GuB mcdrh |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0008026 | ATP-dependent helicase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7205856009 | 0.2703707458 | 0.9999902473 | 0.9942796591 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3760209692 |
| GSE13712_SHEAR | Up | 0.0759457628 |
| GSE13712_STATIC | Down | -0.0141367404 |
| GSE19018 | Up | 0.2138275859 |
| GSE19899_A1 | Up | 0.1123710928 |
| GSE19899_A2 | Up | 0.1858854472 |
| PubMed_21979375_A1 | Up | 0.4297493204 |
| PubMed_21979375_A2 | Up | 0.5447472302 |
| GSE35957 | Down | -0.3924840994 |
| GSE36640 | Down | -0.1616990338 |
| GSE54402 | Up | 0.0825963290 |
| GSE9593 | Down | -0.3355186649 |
| GSE43922 | Up | 0.0268565421 |
| GSE24585 | Up | 0.0119473460 |
| GSE37065 | Down | -0.1738870428 |
| GSE28863_A1 | Up | 0.0022771257 |
| GSE28863_A2 | Up | 0.3244977059 |
| GSE28863_A3 | Down | -0.6669703475 |
| GSE28863_A4 | Down | -0.1070091378 |
| GSE48662 | Down | -0.3193454026 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT023132 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-1 | MIMAT0000416 | MIRT024089 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024678 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026875 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028640 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028640 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT046014 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
