HCSGD entry for MIS12
1. General information
| Official gene symbol | MIS12 |
|---|---|
| Entrez ID | 79003 |
| Gene full name | MIS12, MIND kinetochore complex component, homolog (S. pombe) |
| Other gene symbols | 2510025F08Rik KNTC2AP MTW1 hMis12 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0000444 | MIS12/MIND type complex | IDA | cellular_component |
| GO:0000775 | Chromosome, centromeric region | IEA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0007059 | Chromosome segregation | IMP | biological_process |
| GO:0007067 | Mitosis | IEA | biological_process |
| GO:0051382 | Kinetochore assembly | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9465932145 | 0.0116625394 | 0.9999902473 | 0.2131895139 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0985150210 |
| GSE13712_SHEAR | Down | -0.1829347057 |
| GSE13712_STATIC | Down | -0.4469522081 |
| GSE19018 | Down | -1.4923309400 |
| GSE19899_A1 | Down | -0.1724229024 |
| GSE19899_A2 | Down | -0.6887005760 |
| PubMed_21979375_A1 | Down | -0.0914431874 |
| PubMed_21979375_A2 | Down | -0.8616071551 |
| GSE35957 | Down | -0.6435920723 |
| GSE36640 | Down | -1.0083231232 |
| GSE54402 | Up | 0.1925450601 |
| GSE9593 | Down | -0.7080700502 |
| GSE43922 | Down | -0.0168542803 |
| GSE24585 | Up | 0.1091821291 |
| GSE37065 | Up | 0.3561895851 |
| GSE28863_A1 | Down | -0.0024132516 |
| GSE28863_A2 | Down | -0.0253856027 |
| GSE28863_A3 | Down | -0.2998672495 |
| GSE28863_A4 | Up | 0.2034635607 |
| GSE48662 | Down | -0.5289349282 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-192-5p | MIMAT0000222 | MIRT004855 | Luciferase reporter assay//qRT-PCR//Reporter assay;Microarray;Other | Functional MTI | 19074876 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024957 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-32-5p | MIMAT0000090 | MIRT028251 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047693 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051265 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
