HCSGD entry for SLC25A20

1. General information

Official gene symbolSLC25A20
Entrez ID788
Gene full namesolute carrier family 25 (carnitine/acylcarnitine translocase), member 20
Other gene symbolsCAC CACT
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005737CytoplasmIDAcellular_component
GO:0005739MitochondrionIDAcellular_component
GO:0005743Mitochondrial inner membraneIEA TAScellular_component
GO:0006810TransportIEAbiological_process
GO:0006853Carnitine shuttleTASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0044255Cellular lipid metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00101371150.98342103640.08642076681.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.6899981960
GSE13712_SHEARUp0.6716984901
GSE13712_STATICUp0.7612053497
GSE19018Down-0.1651008028
GSE19899_A1Up1.3590872742
GSE19899_A2Up1.3126318685
PubMed_21979375_A1Up0.7591060943
PubMed_21979375_A2Up2.2139934714
GSE35957Up0.2772651442
GSE36640Up1.9010881121
GSE54402Up0.2615771195
GSE9593Up0.0549059862
GSE43922Up1.1101081881
GSE24585Up0.5237691198
GSE37065Up0.2193998614
GSE28863_A1Down-0.1452008320
GSE28863_A2Down-0.0833061098
GSE28863_A3Down-0.2521331721
GSE28863_A4Up0.1331480698
GSE48662Down-0.1854455547

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

L-CarnitineDB00583 APRD01070

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 2 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

25797700We investigated whether vascular endothelial growth factor (VEGF) signaling via its receptor, VEGFR2, regulates senescence and proliferation of tumor cells in mice with colitis-associated cancer (CAC)
25797700METHODS: CAC was induced in VEGFR2(DeltaIEC) mice, which do not express VEGFR2 in the intestinal epithelium, and VEGFR2(fl/fl) mice (controls) by administration of azoxymethane followed by dextran sodium sulfate
21486281L-NIO partially blunted and c-PTIO prevented NCX 547-induced improvements in CAC functions
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