HCSGD entry for SCG2

1. General information

Official gene symbolSCG2
Entrez ID7857
Gene full namesecretogranin II
Other gene symbolsCHGC EM66 SN SgII
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000165MAPK cascadeIDAbiological_process
GO:0001525AngiogenesisIDA IEAbiological_process
GO:0001937Negative regulation of endothelial cell proliferationTASbiological_process
GO:0001938Positive regulation of endothelial cell proliferationIDAbiological_process
GO:0005125Cytokine activityIDAmolecular_function
GO:0005615Extracellular spaceIDAcellular_component
GO:0006928Cellular component movementIDAbiological_process
GO:0006954Inflammatory responseTASbiological_process
GO:0009306Protein secretionTASbiological_process
GO:0030141Secretory granuleIEAcellular_component
GO:0035556Intracellular signal transductionIDAbiological_process
GO:0042056Chemoattractant activityIDAmolecular_function
GO:0043542Endothelial cell migrationTASbiological_process
GO:0048245Eosinophil chemotaxisIDAbiological_process
GO:0050918Positive chemotaxisIDAbiological_process
GO:0050930Induction of positive chemotaxisIDAbiological_process
GO:2000352Negative regulation of endothelial cell apoptotic processIDAbiological_process
GO:2001237Negative regulation of extrinsic apoptotic signaling pathwayIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00683453140.01619571820.21616630700.2481300931

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up2.1543314010
GSE13712_SHEARUp0.4614106041
GSE13712_STATICUp0.3510853331
GSE19018Down-0.0889449867
GSE19899_A1Down-0.6822763640
GSE19899_A2Down-3.1787979188
PubMed_21979375_A1Down-1.8759752322
PubMed_21979375_A2Down-1.6283394863
GSE35957Down-0.2955230595
GSE36640Up3.8286122805
GSE54402Down-2.9733469443
GSE9593Up2.7526906951
GSE43922Down-0.2989161648
GSE24585Down-0.0406327112
GSE37065Up1.7191537434
GSE28863_A1Down-0.0890617845
GSE28863_A2Up0.5624284231
GSE28863_A3Up0.3400142409
GSE28863_A4Down-0.0594804911
GSE48662Down-0.0637089203

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-98-5pMIMAT0000096MIRT027788MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.