HCSGD entry for CACNB3
1. General information
| Official gene symbol | CACNB3 |
|---|---|
| Entrez ID | 784 |
| Gene full name | calcium channel, voltage-dependent, beta 3 subunit |
| Other gene symbols | CAB3 CACNLB3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005245 | Voltage-gated calcium channel activity | IDA IEA | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005891 | Voltage-gated calcium channel complex | IDA IEA | cellular_component |
| GO:0006810 | Transport | TAS | biological_process |
| GO:0006816 | Calcium ion transport | IDA | biological_process |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0007411 | Axon guidance | TAS | biological_process |
| GO:0016020 | Membrane | IDA | cellular_component |
| GO:0016324 | Apical plasma membrane | IEA | cellular_component |
| GO:0019901 | Protein kinase binding | IEA | molecular_function |
| GO:0050852 | T cell receptor signaling pathway | IEA | biological_process |
| GO:0051899 | Membrane depolarization | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9317554120 | 0.1002658562 | 0.9999902473 | 0.6069681693 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0216275372 |
| GSE13712_SHEAR | Down | -0.4706525754 |
| GSE13712_STATIC | Down | -0.2191501045 |
| GSE19018 | Down | -0.1150060026 |
| GSE19899_A1 | Down | -0.0764481577 |
| GSE19899_A2 | Down | -0.2740710800 |
| PubMed_21979375_A1 | Down | -0.2940983100 |
| PubMed_21979375_A2 | Up | 0.2226749742 |
| GSE35957 | Down | -0.6379766612 |
| GSE36640 | Down | -0.0888937237 |
| GSE54402 | Down | -0.5138127251 |
| GSE9593 | Down | -0.1729845539 |
| GSE43922 | Down | -0.0521450005 |
| GSE24585 | Up | 0.4312294033 |
| GSE37065 | Down | -0.2512021614 |
| GSE28863_A1 | Up | 0.1163960327 |
| GSE28863_A2 | Up | 0.1814408368 |
| GSE28863_A3 | Down | -0.1253680199 |
| GSE28863_A4 | Down | -0.1299427936 |
| GSE48662 | Up | 0.0354293613 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Verapamil | DB00661 | APRD00335 |
| Mibefradil | DB01388 | - |
| Dronedarone | DB04855 | - |
| Spironolactone | DB00421 | APRD01234 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT016710 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-196b-5p | MIMAT0001080 | MIRT042695 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
