HCSGD entry for EVI5
1. General information
| Official gene symbol | EVI5 |
|---|---|
| Entrez ID | 7813 |
| Gene full name | ecotropic viral integration site 5 |
| Other gene symbols | NB4S |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005097 | Rab GTPase activator activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005815 | Microtubule organizing center | IEA | cellular_component |
| GO:0005819 | Spindle | IEA | cellular_component |
| GO:0007049 | Cell cycle | IEA | biological_process |
| GO:0007275 | Multicellular organismal development | TAS | biological_process |
| GO:0008283 | Cell proliferation | TAS | biological_process |
| GO:0051301 | Cell division | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1054030622 | 0.8585075871 | 0.6742899878 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0467937833 |
| GSE13712_SHEAR | Up | 0.0739128445 |
| GSE13712_STATIC | Up | 0.0824483411 |
| GSE19018 | Up | 0.0824946955 |
| GSE19899_A1 | Down | -0.0048228790 |
| GSE19899_A2 | Up | 0.4070253669 |
| PubMed_21979375_A1 | Up | 0.1921551528 |
| PubMed_21979375_A2 | Up | 0.0283889206 |
| GSE35957 | Up | 0.4609469387 |
| GSE36640 | Up | 0.4187373620 |
| GSE54402 | Down | -0.0448867020 |
| GSE9593 | Up | 0.1903386618 |
| GSE43922 | Down | -0.2002063645 |
| GSE24585 | Up | 0.4694613519 |
| GSE37065 | Down | -0.0237429810 |
| GSE28863_A1 | Up | 0.5292155947 |
| GSE28863_A2 | Up | 0.4945078720 |
| GSE28863_A3 | Down | -0.3481340900 |
| GSE28863_A4 | Down | -0.3917231680 |
| GSE48662 | Up | 0.2062702942 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022914 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-96-5p | MIMAT0000095 | MIRT027925 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-182-5p | MIMAT0000259 | MIRT047210 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 15236317 | The candidate genes PRKCL2 and GTF2B, within SRO2, and TGFBR3, CDC7, and EVI5, in a broad region encompassing SRO3, were screened in 1p22-linked melanoma kindreds, but no coding mutations were detected |
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