HCSGD entry for CACNA1E


1. General information

Official gene symbolCACNA1E
Entrez ID777
Gene full namecalcium channel, voltage-dependent, R type, alpha 1E subunit
Other gene symbolsBII CACH6 CACNL1A6 Cav2.3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005245Voltage-gated calcium channel activityIDA IEAmolecular_function
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005891Voltage-gated calcium channel complexIEAcellular_component
GO:0006112Energy reserve metabolic processTASbiological_process
GO:0006810TransportTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0050796Regulation of insulin secretionTASbiological_process
GO:0051899Membrane depolarizationTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.81804597090.77698052890.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0003813227
GSE13712_SHEARDown-0.0953334838
GSE13712_STATICDown-0.0244977420
GSE19018Up0.0957546519
GSE19899_A1Up0.1189638696
GSE19899_A2Up0.1111185871
PubMed_21979375_A1Up0.0653091784
PubMed_21979375_A2Up0.0205003259
GSE35957Up0.1682799927
GSE36640Up0.0268685657
GSE54402Up0.0451535734
GSE9593Up0.0357458349
GSE43922Up0.0156482577
GSE24585Down-0.0103820021
GSE37065Down-0.0733447292
GSE28863_A1Down-0.1596535689
GSE28863_A2Down-0.1480274179
GSE28863_A3Up0.3022842846
GSE28863_A4Down-0.1800970097
GSE48662Down-0.0367361597

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.