HCSGD entry for ZKSCAN8


1. General information

Official gene symbolZKSCAN8
Entrez ID7745
Gene full namezinc finger with KRAB and SCAN domains 8
Other gene symbolsLD5-1 ZNF192 ZSCAN40
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003677DNA bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005634NucleusIDA IEAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.44710668290.48348468140.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0043846562
GSE13712_SHEARDown-0.0590759627
GSE13712_STATICDown-0.0735921826
GSE19018Up0.0898170622
GSE19899_A1Down-0.0037266832
GSE19899_A2Down-0.4032000735
PubMed_21979375_A1Down-0.1484152075
PubMed_21979375_A2Up0.0025004635
GSE35957Up0.0750506761
GSE36640Down-0.0178263023
GSE54402Up0.0225294981
GSE9593Up0.1162920859
GSE43922Down-0.4410244668
GSE24585Up0.4078672080
GSE37065Up0.2179122646
GSE28863_A1Up0.4594698381
GSE28863_A2Up0.4257783730
GSE28863_A3Down-0.2645787819
GSE28863_A4Down-0.3366212876
GSE48662Up0.2213279612

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018290MicroarrayFunctional MTI (Weak)18185580
hsa-miR-221-3pMIMAT0000278MIRT024197SequencingFunctional MTI (Weak)20371350
hsa-miR-98-5pMIMAT0000096MIRT027721MicroarrayFunctional MTI (Weak)19088304
hsa-miR-877-5pMIMAT0004949MIRT037331CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.