HCSGD entry for ZNF189


1. General information

Official gene symbolZNF189
Entrez ID7743
Gene full namezinc finger protein 189
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterTASbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityTASmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.86317679040.05556222790.99999024730.4437290264

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2404299186
GSE13712_SHEARDown-0.6020465223
GSE13712_STATICDown-0.5221441580
GSE19018Down-0.4157827592
GSE19899_A1Down-0.2588844884
GSE19899_A2Down-0.2720772989
PubMed_21979375_A1Down-0.0791051212
PubMed_21979375_A2Up0.2408946648
GSE35957Up0.1175716396
GSE36640Down-0.0919575976
GSE54402Up0.0238570055
GSE9593Down-0.2586138353
GSE43922Down-0.0094054003
GSE24585Up0.1214119529
GSE37065Up0.1003382133
GSE28863_A1Down-0.0137674862
GSE28863_A2Down-0.0356384858
GSE28863_A3Down-0.9899265770
GSE28863_A4Up0.1519538941
GSE48662Down-0.0201796175

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.