HCSGD entry for ZBTB16

1. General information

Official gene symbolZBTB16
Entrez ID7704
Gene full namezinc finger and BTB domain containing 16
Other gene symbolsPLZF ZNF145
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001501Skeletal system developmentIEAbiological_process
GO:0001823Mesonephros developmentIEA ISSbiological_process
GO:0003677DNA bindingIDA NASmolecular_function
GO:0003690Double-stranded DNA bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005829CytosolIEAcellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006915Apoptotic processNASbiological_process
GO:0007417Central nervous system developmentIEA ISSbiological_process
GO:0008022Protein C-terminus bindingIEAmolecular_function
GO:0008285Negative regulation of cell proliferationIEAbiological_process
GO:0009880Embryonic pattern specificationIEAbiological_process
GO:0009952Anterior/posterior pattern specificationIEAbiological_process
GO:0016567Protein ubiquitinationIEAbiological_process
GO:0016604Nuclear bodyIDAcellular_component
GO:0016605PML bodyIDAcellular_component
GO:0016607Nuclear speckIDAcellular_component
GO:0017053Transcriptional repressor complexIDAcellular_component
GO:0019904Protein domain specific bindingIEAmolecular_function
GO:0030097HemopoiesisIDA IEA TASbiological_process
GO:0030099Myeloid cell differentiationTASbiological_process
GO:0032332Positive regulation of chondrocyte differentiationIMPbiological_process
GO:0034504Protein localization to nucleusIEAbiological_process
GO:0035116Embryonic hindlimb morphogenesisIEAbiological_process
GO:0035136Forelimb morphogenesisIEAbiological_process
GO:0042733Embryonic digit morphogenesisIEAbiological_process
GO:0042802Identical protein bindingIPImolecular_function
GO:0042803Protein homodimerization activityIDAmolecular_function
GO:0043065Positive regulation of apoptotic processIEAbiological_process
GO:0045600Positive regulation of fat cell differentiationIMPbiological_process
GO:0045638Negative regulation of myeloid cell differentiationIEA ISSbiological_process
GO:0045778Positive regulation of ossificationIDAbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedIDA NASbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedIDAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0048133Male germ-line stem cell divisionIEAbiological_process
GO:0051216Cartilage developmentIDAbiological_process
GO:0061036Positive regulation of cartilage developmentIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.60764121420.20854241860.99999024730.8841889497

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0367383278
GSE13712_SHEARDown-0.9472541821
GSE13712_STATICDown-1.5585379363
GSE19018Up0.1762598690
GSE19899_A1Up0.1669180369
GSE19899_A2Up0.0674689172
PubMed_21979375_A1Down-0.0146099075
PubMed_21979375_A2Down-0.0295444818
GSE35957Up0.2012484570
GSE36640Up0.0010571632
GSE54402Up0.0578932821
GSE9593Up0.1330865354
GSE43922Up0.0443925854
GSE24585Down-0.1020118140
GSE37065Down-0.0608283744
GSE28863_A1Up0.0547803015
GSE28863_A2Down-0.1174614471
GSE28863_A3Up0.0616091128
GSE28863_A4Up0.0560706136
GSE48662Up0.0603287638

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.