HCSGD entry for CNBP
1. General information
| Official gene symbol | CNBP |
|---|---|
| Entrez ID | 7555 |
| Gene full name | CCHC-type zinc finger, nucleic acid binding protein |
| Other gene symbols | CNBP1 DM2 PROMM RNF163 ZCCHC22 ZNF9 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0003697 | Single-stranded DNA binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | TAS | molecular_function |
| GO:0003727 | Single-stranded RNA binding | IEA | molecular_function |
| GO:0005634 | Nucleus | ISS | cellular_component |
| GO:0005783 | Endoplasmic reticulum | ISS | cellular_component |
| GO:0005829 | Cytosol | ISS | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | TAS | biological_process |
| GO:0006695 | Cholesterol biosynthetic process | TAS | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0008284 | Positive regulation of cell proliferation | ISS | biological_process |
| GO:0045893 | Positive regulation of transcription, DNA-templated | ISS | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1419896243 | 0.8902831541 | 0.7565484008 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4945948701 |
| GSE13712_SHEAR | Up | 0.4303639895 |
| GSE13712_STATIC | Up | 0.1147060238 |
| GSE19018 | Down | -0.1529211622 |
| GSE19899_A1 | Up | 0.0692892802 |
| GSE19899_A2 | Up | 0.5520343756 |
| PubMed_21979375_A1 | Up | 0.6787903993 |
| PubMed_21979375_A2 | Up | 0.4984937348 |
| GSE35957 | Up | 0.0162979034 |
| GSE36640 | Down | -0.1046241836 |
| GSE54402 | Down | -0.0801323440 |
| GSE9593 | Up | 0.1984821920 |
| GSE43922 | Up | 0.0039693765 |
| GSE24585 | Down | -0.0156700273 |
| GSE37065 | Up | 0.1997643217 |
| GSE28863_A1 | Up | 0.0635520006 |
| GSE28863_A2 | Up | 0.3330531251 |
| GSE28863_A3 | Down | -0.2344969706 |
| GSE28863_A4 | Down | -0.2923216313 |
| GSE48662 | Down | -0.0380552914 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-877-3p | MIMAT0004950 | MIRT036825 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT044933 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-26a-5p | MIMAT0000082 | MIRT050198 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051588 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052598 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 20615871 | The mature form of sterol regulatory element-binding protein (SREBP)-1 was also elevated |
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