HCSGD entry for ZIC3


1. General information

Official gene symbolZIC3
Entrez ID7547
Gene full nameZic family member 3
Other gene symbolsHTX HTX1 VACTERLX ZNF203
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001947Heart loopingIMPbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusISScellular_component
GO:0005737CytoplasmISScellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0007368Determination of left/right symmetryIMPbiological_process
GO:0009952Anterior/posterior pattern specificationIEAbiological_process
GO:0030154Cell differentiationIEAbiological_process
GO:0030324Lung developmentIMPbiological_process
GO:0035469Determination of pancreatic left/right asymmetryIMPbiological_process
GO:0035545Determination of left/right asymmetry in nervous systemIEAbiological_process
GO:0043565Sequence-specific DNA bindingIDAmolecular_function
GO:0045893Positive regulation of transcription, DNA-templatedISSbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0071907Determination of digestive tract left/right asymmetryIMPbiological_process
GO:0071910Determination of liver left/right asymmetryIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.65889967710.80212161010.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0395995913
GSE13712_SHEARUp0.0037391372
GSE13712_STATICUp0.0705287563
GSE19018Down-0.0283419672
GSE19899_A1Up0.1690496489
GSE19899_A2Up0.1311838317
PubMed_21979375_A1Down-0.1378786505
PubMed_21979375_A2Down-0.1593472492
GSE35957Up0.0801503642
GSE36640Up0.0909382360
GSE54402Up0.0087452703
GSE9593Up0.1376459700
GSE43922Up0.0146693892
GSE24585Up0.1512331610
GSE37065Up0.0021164876
GSE28863_A1Down-0.1380654794
GSE28863_A2Down-0.0658445183
GSE28863_A3Up0.2303068973
GSE28863_A4Up0.0340295867
GSE48662Down-0.0404086518

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-155-5pMIMAT0000646MIRT000976Luciferase reporter assayFunctional MTI18367535
hsa-miR-155-5pMIMAT0000646MIRT000976Luciferase reporter assayFunctional MTI19177201
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.