HCSGD entry for PTTG1IP
1. General information
| Official gene symbol | PTTG1IP |
|---|---|
| Entrez ID | 754 |
| Gene full name | pituitary tumor-transforming 1 interacting protein |
| Other gene symbols | C21orf1 C21orf3 PBF |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003674 | Molecular_function | ND | molecular_function |
| GO:0004872 | Receptor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006606 | Protein import into nucleus | IDA | biological_process |
| GO:0007275 | Multicellular organismal development | IEA | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1031082938 | 0.9191912997 | 0.6679673148 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1056209143 |
| GSE13712_SHEAR | Up | 0.0894326788 |
| GSE13712_STATIC | Up | 0.0590704130 |
| GSE19018 | Up | 0.4366505171 |
| GSE19899_A1 | Down | -0.1663212349 |
| GSE19899_A2 | Up | 0.2440784120 |
| PubMed_21979375_A1 | Up | 0.1074747349 |
| PubMed_21979375_A2 | Up | 0.0880345205 |
| GSE35957 | Up | 0.2581360040 |
| GSE36640 | Up | 0.2124516687 |
| GSE54402 | Down | -0.4643636976 |
| GSE9593 | Up | 0.2974493105 |
| GSE43922 | Up | 0.0652364253 |
| GSE24585 | Up | 0.0915488068 |
| GSE37065 | Down | -0.0408947010 |
| GSE28863_A1 | Up | 0.4613308002 |
| GSE28863_A2 | Up | 0.4275937062 |
| GSE28863_A3 | Up | 0.1207586439 |
| GSE28863_A4 | Down | -0.0175395564 |
| GSE48662 | Up | 0.5110428626 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT002596 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT002596 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027698 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
