HCSGD entry for YWHAH
1. General information
| Official gene symbol | YWHAH |
|---|---|
| Entrez ID | 7533 |
| Gene full name | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide |
| Other gene symbols | YWHA1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002028 | Regulation of sodium ion transport | IDA | biological_process |
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005159 | Insulin-like growth factor receptor binding | ISS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | ISS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006713 | Glucocorticoid catabolic process | IDA | biological_process |
| GO:0006886 | Intracellular protein transport | ISS | biological_process |
| GO:0006915 | Apoptotic process | TAS | biological_process |
| GO:0014704 | Intercalated disc | IC | cellular_component |
| GO:0017080 | Sodium channel regulator activity | IDA | molecular_function |
| GO:0019899 | Enzyme binding | IPI | molecular_function |
| GO:0019904 | Protein domain specific binding | IEA ISS | molecular_function |
| GO:0030659 | Cytoplasmic vesicle membrane | TAS | cellular_component |
| GO:0035259 | Glucocorticoid receptor binding | IPI | molecular_function |
| GO:0042921 | Glucocorticoid receptor signaling pathway | IDA | biological_process |
| GO:0044325 | Ion channel binding | IPI | molecular_function |
| GO:0045664 | Regulation of neuron differentiation | ISS | biological_process |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0046982 | Protein heterodimerization activity | IPI | molecular_function |
| GO:0048167 | Regulation of synaptic plasticity | ISS | biological_process |
| GO:0050774 | Negative regulation of dendrite morphogenesis | ISS | biological_process |
| GO:0070062 | Extracellular vesicular exosome | IDA | cellular_component |
| GO:0086010 | Membrane depolarization during action potential | IDA | biological_process |
| GO:0097193 | Intrinsic apoptotic signaling pathway | TAS | biological_process |
| GO:1900740 | Positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway | TAS | biological_process |
| GO:2000649 | Regulation of sodium ion transmembrane transporter activity | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8908855743 | 0.1384449185 | 0.9999902473 | 0.7163374681 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3319046071 |
| GSE13712_SHEAR | Up | 0.2865331522 |
| GSE13712_STATIC | Up | 0.1572181813 |
| GSE19018 | Up | 0.1604848887 |
| GSE19899_A1 | Down | -0.0287257201 |
| GSE19899_A2 | Down | -0.1030747399 |
| PubMed_21979375_A1 | Down | -0.6568236125 |
| PubMed_21979375_A2 | Down | -0.0121505261 |
| GSE35957 | Down | -0.2236992319 |
| GSE36640 | Down | -0.7908279053 |
| GSE54402 | Down | -0.2105681264 |
| GSE9593 | Down | -0.0578019978 |
| GSE43922 | Down | -0.0057352337 |
| GSE24585 | Up | 0.1239988452 |
| GSE37065 | Down | -0.0890964877 |
| GSE28863_A1 | Down | -0.1296019949 |
| GSE28863_A2 | Up | 0.0305992854 |
| GSE28863_A3 | Down | -0.0262000424 |
| GSE28863_A4 | Up | 0.2797142003 |
| GSE48662 | Down | -0.5062485783 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-186-5p | MIMAT0000456 | MIRT021116 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT021116 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027235 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-33a-5p | MIMAT0000091 | MIRT028247 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-32-5p | MIMAT0000090 | MIRT028327 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT032075 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT032075 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-324-5p | MIMAT0000761 | MIRT043064 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
