HCSGD entry for LDLRAD4
1. General information
| Official gene symbol | LDLRAD4 |
|---|---|
| Entrez ID | 753 |
| Gene full name | low density lipoprotein receptor class A domain containing 4 |
| Other gene symbols | C18orf1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003674 | Molecular_function | ND | molecular_function |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0008150 | Biological_process | ND | biological_process |
| GO:0016021 | Integral component of membrane | NAS | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8324122678 | 0.4139040424 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0231429832 |
| GSE13712_SHEAR | Down | -0.3649354627 |
| GSE13712_STATIC | Down | -0.2791786433 |
| GSE19018 | Down | -0.1357006150 |
| GSE19899_A1 | Up | 0.0446405980 |
| GSE19899_A2 | Down | -0.0636371608 |
| PubMed_21979375_A1 | Up | 0.0908152519 |
| PubMed_21979375_A2 | Down | -0.1001060311 |
| GSE35957 | Down | -0.0715153811 |
| GSE36640 | Up | 0.4538225068 |
| GSE54402 | Down | -0.0243353380 |
| GSE9593 | Down | -0.1028652269 |
| GSE43922 | Up | 0.1050347160 |
| GSE24585 | Down | -0.2277803323 |
| GSE37065 | Up | 0.1192464492 |
| GSE28863_A1 | Down | -0.1620964031 |
| GSE28863_A2 | Down | -0.1779392535 |
| GSE28863_A3 | Up | 0.1915239292 |
| GSE28863_A4 | Up | 0.0576702505 |
| GSE48662 | Up | 0.1651124683 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017628 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022560 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 21448135 | Gene-expression profiling revealed a >100-fold increase in the levels of the transcription factor and putative tumour suppressor gene TGFbeta-stimulated clone 22 (TSC22D1) in BRAF(E600)-induced senescence, in both human fibroblasts and melanocytes |
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