HCSGD entry for FMNL1


1. General information

Official gene symbolFMNL1
Entrez ID752
Gene full nameformin-like 1
Other gene symbolsC17orf1 C17orf1B FHOD4 FMNL KW-13
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003674Molecular_functionNDmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005522Profilin bindingIEAmolecular_function
GO:0005829CytosolISScellular_component
GO:0005886Plasma membraneISScellular_component
GO:0005938Cell cortexIEAcellular_component
GO:0006929Substrate-dependent cell migrationIEAbiological_process
GO:0007010Cytoskeleton organizationIEAbiological_process
GO:0008360Regulation of cell shapeIEA IMPbiological_process
GO:0030866Cortical actin cytoskeleton organizationIMPbiological_process
GO:0032059BlebIEAcellular_component
GO:0032794GTPase activating protein bindingIDAmolecular_function
GO:0045335Phagocytic vesicleISScellular_component
GO:0048365Rac GTPase bindingISSmolecular_function
GO:0051014Actin filament severingISSbiological_process
GO:0051015Actin filament bindingISSmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.34125673040.87210875350.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0632590249
GSE13712_SHEARUp0.0770273252
GSE13712_STATICUp0.0206423622
GSE19018Up0.3148531823
GSE19899_A1Down-0.1573430413
GSE19899_A2Up0.1731085888
PubMed_21979375_A1Up0.1406076503
PubMed_21979375_A2Down-0.1310566157
GSE35957Up0.0817961158
GSE36640Down-0.0626430778
GSE54402Up0.1305331181
GSE9593Up0.1210452290
GSE43922Up0.0499033216
GSE24585Up0.0815915455
GSE37065Down-0.0563860332
GSE28863_A1Down-0.0995960922
GSE28863_A2Down-0.0084122135
GSE28863_A3Up0.4539890282
GSE28863_A4Up0.0763846759
GSE48662Up0.1463377335

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.