HCSGD entry for WNT8B

1. General information

Official gene symbolWNT8B
Entrez ID7479
Gene full namewingless-type MMTV integration site family, member 8B
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005109Frizzled bindingIBAmolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005578Proteinaceous extracellular matrixIEAcellular_component
GO:0005615Extracellular spaceIBAcellular_component
GO:0007165Signal transductionTASbiological_process
GO:0007369GastrulationISSbiological_process
GO:0007399Nervous system developmentTASbiological_process
GO:0010628Positive regulation of gene expressionIEAbiological_process
GO:0010629Negative regulation of gene expressionIEAbiological_process
GO:0016055Wnt signaling pathwayIBAbiological_process
GO:0030182Neuron differentiationIBA ISSbiological_process
GO:0032355Response to estradiolNASbiological_process
GO:0032526Response to retinoic acidNASbiological_process
GO:0045165Cell fate commitmentIBAbiological_process
GO:0048263Determination of dorsal identityISSbiological_process
GO:0071300Cellular response to retinoic acidISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.40461852130.83291827060.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1449448464
GSE13712_SHEARDown-0.0418339163
GSE13712_STATICUp0.0193649353
GSE19018Up0.2267238757
GSE19899_A1Up0.2256127036
GSE19899_A2Up0.1075699993
PubMed_21979375_A1Up0.0278608143
PubMed_21979375_A2Down-0.1745468101
GSE35957Up0.2008222995
GSE36640Up0.0769197312
GSE54402Down-0.0190860699
GSE9593Up0.0314339299
GSE43922Up0.0167157129
GSE24585Down-0.1263775760
GSE37065Up0.1178260831
GSE28863_A1Down-0.2566027842
GSE28863_A2Up0.1096528842
GSE28863_A3Up0.2751938820
GSE28863_A4Up0.1990250932
GSE48662Up0.1054907791

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-7-5pMIMAT0000252MIRT025654MicroarrayFunctional MTI (Weak)17612493
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.