HCSGD entry for WNT3

1. General information

Official gene symbolWNT3
Entrez ID7473
Gene full namewingless-type MMTV integration site family, member 3
Other gene symbolsINT4
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000902Cell morphogenesisIMPbiological_process
GO:0001707Mesoderm formationIEAbiological_process
GO:0005109Frizzled bindingIPImolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005578Proteinaceous extracellular matrixIEAcellular_component
GO:0005615Extracellular spaceTAScellular_component
GO:0005788Endoplasmic reticulum lumenTAScellular_component
GO:0005796Golgi lumenTAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0007411Axon guidanceIEAbiological_process
GO:0009948Anterior/posterior axis specificationIEAbiological_process
GO:0009950Dorsal/ventral axis specificationIEAbiological_process
GO:0010469Regulation of receptor activityICbiological_process
GO:0010628Positive regulation of gene expressionIEAbiological_process
GO:0019904Protein domain specific bindingIEAmolecular_function
GO:0030182Neuron differentiationIBA ISSbiological_process
GO:0035115Embryonic forelimb morphogenesisIEAbiological_process
GO:0035116Embryonic hindlimb morphogenesisIEAbiological_process
GO:0044338Canonical Wnt signaling pathway involved in mesenchymal stem cell differentiationIMPbiological_process
GO:0044339Canonical Wnt signaling pathway involved in osteoblast differentiationIMPbiological_process
GO:0045165Cell fate commitmentIBAbiological_process
GO:0048018Receptor agonist activityICmolecular_function
GO:0048697Positive regulation of collateral sprouting in absence of injuryIEAbiological_process
GO:0048843Negative regulation of axon extension involved in axon guidanceIEAbiological_process
GO:0060064Spemann organizer formation at the anterior end of the primitive streakIEAbiological_process
GO:0060070Canonical Wnt signaling pathwayIDAbiological_process
GO:0060174Limb bud formationIMPbiological_process
GO:0060323Head morphogenesisIEAbiological_process
GO:0061180Mammary gland epithelium developmentIEPbiological_process
GO:0071300Cellular response to retinoic acidISSbiological_process
GO:2000273Positive regulation of receptor activityICbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.73562361230.84659645910.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Down-0.3102677632
GSE28863_A2Down-0.1765492565
GSE28863_A3Up0.1679630813
GSE28863_A4Up0.1541617428
GSE48662Up0.3083232910

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018503MicroarrayFunctional MTI (Weak)18185580
hsa-miR-215-5pMIMAT0000272MIRT024672MicroarrayFunctional MTI (Weak)19074876
hsa-miR-192-5pMIMAT0000222MIRT026683MicroarrayFunctional MTI (Weak)19074876
hsa-miR-1301-3pMIMAT0005797MIRT036062CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.