HCSGD entry for WIPF1
1. General information
| Official gene symbol | WIPF1 |
|---|---|
| Entrez ID | 7456 |
| Gene full name | WAS/WASL interacting protein family, member 1 |
| Other gene symbols | PRPL-2 WASPIP WIP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001726 | Ruffle | IEA | cellular_component |
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005522 | Profilin binding | TAS | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005884 | Actin filament | IEA | cellular_component |
| GO:0006461 | Protein complex assembly | TAS | biological_process |
| GO:0008154 | Actin polymerization or depolymerization | IEA | biological_process |
| GO:0015629 | Actin cytoskeleton | IEA TAS | cellular_component |
| GO:0016023 | Cytoplasmic membrane-bounded vesicle | IEA | cellular_component |
| GO:0030048 | Actin filament-based movement | IEA | biological_process |
| GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | TAS | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0051707 | Response to other organism | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1376990046 | 0.5081247635 | 0.7474480305 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2641858554 |
| GSE13712_SHEAR | Up | 0.0270403439 |
| GSE13712_STATIC | Up | 0.1306276521 |
| GSE19018 | Up | 0.3762457285 |
| GSE19899_A1 | Up | 0.0065280787 |
| GSE19899_A2 | Down | -0.0955339051 |
| PubMed_21979375_A1 | Up | 0.0060593241 |
| PubMed_21979375_A2 | Up | 0.6955335817 |
| GSE35957 | Down | -0.3973656238 |
| GSE36640 | Down | -0.2002958524 |
| GSE54402 | Up | 0.1378202085 |
| GSE9593 | Down | -0.3398110095 |
| GSE43922 | Up | 0.3355900462 |
| GSE24585 | Up | 0.4053969190 |
| GSE37065 | Up | 0.1766926628 |
| GSE28863_A1 | Up | 0.4495836473 |
| GSE28863_A2 | Up | 0.5387464544 |
| GSE28863_A3 | Up | 0.0940054881 |
| GSE28863_A4 | Down | -0.4450172645 |
| GSE48662 | Down | -0.2627683401 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-15a-5p | MIMAT0000068 | MIRT003872 | Microarray | Functional MTI (Weak) | 18362358 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT004366 | Microarray | Functional MTI (Weak) | 18362358 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022917 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-15a-5p | MIMAT0000068 | NA | hsa-miR-15a | 18362358 | |||
| hsa-miR-16-5p | MIMAT0000069 | NA | hsa-miR-16 | 18362358 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
