HCSGD entry for VWF

1. General information

Official gene symbolVWF
Entrez ID7450
Gene full namevon Willebrand factor
Other gene symbolsF8VWF VWD
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001889Liver developmentIEAbiological_process
GO:0001890Placenta developmentIEAbiological_process
GO:0001948Glycoprotein bindingIDAmolecular_function
GO:0002020Protease bindingIDA IPImolecular_function
GO:0002576Platelet degranulationTASbiological_process
GO:0005178Integrin bindingIPImolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005518Collagen bindingIDAmolecular_function
GO:0005576Extracellular regionIDA NAS TAScellular_component
GO:0005578Proteinaceous extracellular matrixIEAcellular_component
GO:0005783Endoplasmic reticulumIDAcellular_component
GO:0007155Cell adhesionIDAbiological_process
GO:0007596Blood coagulationIMP TASbiological_process
GO:0007597Blood coagulation, intrinsic pathwayTASbiological_process
GO:0007599HemostasisIMPbiological_process
GO:0009611Response to woundingTASbiological_process
GO:0009897External side of plasma membraneIEAcellular_component
GO:0019865Immunoglobulin bindingIDAmolecular_function
GO:0030168Platelet activationIDA NAS TASbiological_process
GO:0031012Extracellular matrixIDAcellular_component
GO:0031091Platelet alpha granuleNAScellular_component
GO:0031093Platelet alpha granule lumenTAScellular_component
GO:0031589Cell-substrate adhesionIDAbiological_process
GO:0033093Weibel-Palade bodyIDAcellular_component
GO:0042802Identical protein bindingIPImolecular_function
GO:0042803Protein homodimerization activityIDAmolecular_function
GO:0047485Protein N-terminus bindingIPImolecular_function
GO:0051087Chaperone bindingIDAmolecular_function
GO:0051260Protein homooligomerizationIDAbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.53549036510.84093836480.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0131449006
GSE13712_SHEARDown-0.4474691204
GSE13712_STATICUp0.1935851728
GSE19018Up0.0814345178
GSE19899_A1Down-0.0414213937
GSE19899_A2Up0.0478640644
PubMed_21979375_A1Down-0.0863238618
PubMed_21979375_A2Up0.0203669180
GSE35957Up0.2160863747
GSE36640Up0.1290297647
GSE54402Down-0.0892349138
GSE9593Up0.0627019467
GSE43922Up0.0114439738
GSE24585Up0.0367417665
GSE37065Up0.0373559060
GSE28863_A1Down-0.0033692431
GSE28863_A2Down-0.1232799940
GSE28863_A3Up0.3720524539
GSE28863_A4Up0.1353970797
GSE48662Down-0.0052749398

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

ARC1779DB05202 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 4 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

2505938654-fold) and von Willebrand factor (5
25057108Nevertheless, immunostains still demonstrated the presence of the lectin Ulex europaeus and von Willebrand factor
20453494Endothelial cell function was assessed by nitric oxide, von Willebrand factor secretion and capillary-like structure formation
19595526In this study we found a significant reversed correlation between the degree of vascular expression of VWF and age at the time of death
19595526The vascular expression of the VWF enables to estimate an individual's age at the time of his death more or less at about 1
Entries Per Page
Displaying Page of