HCSGD entry for TRPV1
1. General information
| Official gene symbol | TRPV1 |
|---|---|
| Entrez ID | 7442 |
| Gene full name | transient receptor potential cation channel, subfamily V, member 1 |
| Other gene symbols | VR1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004888 | Transmembrane signaling receptor activity | ISS | molecular_function |
| GO:0005216 | Ion channel activity | IEA | molecular_function |
| GO:0005231 | Excitatory extracellular ligand-gated ion channel activity | ISS | molecular_function |
| GO:0005262 | Calcium channel activity | TAS | molecular_function |
| GO:0005516 | Calmodulin binding | IEA | molecular_function |
| GO:0005524 | ATP binding | ISS | molecular_function |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006810 | Transport | TAS | biological_process |
| GO:0007166 | Cell surface receptor signaling pathway | TAS | biological_process |
| GO:0007635 | Chemosensory behavior | TAS | biological_process |
| GO:0015278 | Calcium-release channel activity | ISS | molecular_function |
| GO:0016021 | Integral component of membrane | IDA IEA | cellular_component |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0031226 | Intrinsic component of plasma membrane | ISS | cellular_component |
| GO:0032591 | Dendritic spine membrane | IEA | cellular_component |
| GO:0045211 | Postsynaptic membrane | ISS | cellular_component |
| GO:0050955 | Thermoception | IDA | biological_process |
| GO:0070588 | Calcium ion transmembrane transport | ISS | biological_process |
| GO:0071312 | Cellular response to alkaloid | ISS | biological_process |
| GO:0071318 | Cellular response to ATP | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5615668782 | 0.5940766004 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | - | - |
| GSE13712_SHEAR | - | - |
| GSE13712_STATIC | - | - |
| GSE19018 | - | - |
| GSE19899_A1 | - | - |
| GSE19899_A2 | - | - |
| PubMed_21979375_A1 | - | - |
| PubMed_21979375_A2 | - | - |
| GSE35957 | - | - |
| GSE36640 | - | - |
| GSE54402 | - | - |
| GSE9593 | - | - |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Up | 0.8130075436 |
| GSE28863_A2 | Up | 0.5324671763 |
| GSE28863_A3 | Down | -0.4574375188 |
| GSE28863_A4 | Down | -0.4870151009 |
| GSE48662 | Down | -0.0361545772 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Capsaicin | DB06774 | - |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024445 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026638 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051594 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
