HCSGD entry for VIPR2

1. General information

Official gene symbolVIPR2
Entrez ID7434
Gene full namevasoactive intestinal peptide receptor 2
Other gene symbolsC16DUPq36.3 DUP7q36.3 PACAP-R-3 PACAP-R3 VIP-R-2 VPAC2 VPAC2R VPCAP2R
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004930G-protein coupled receptor activityTASmolecular_function
GO:0004999Vasoactive intestinal polypeptide receptor activityIEAmolecular_function
GO:0005886Plasma membraneIEA TAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0007165Signal transductionTASbiological_process
GO:0007190Activation of adenylate cyclase activityIEAbiological_process
GO:0007267Cell-cell signalingTASbiological_process
GO:0016020MembraneIEAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0048662Negative regulation of smooth muscle cell proliferationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.61042308800.92273064850.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0368236699
GSE13712_SHEARDown-0.0143334709
GSE13712_STATICUp0.0195770762
GSE19018Up0.0768265429
GSE19899_A1Up0.0931998121
GSE19899_A2Up0.1382990512
PubMed_21979375_A1Down-0.0681806359
PubMed_21979375_A2Up0.0260730302
GSE35957Up0.1351162753
GSE36640Up0.0093110053
GSE54402Down-0.0512543260
GSE9593Up0.0721031815
GSE43922Up0.0095021698
GSE24585Up0.0255543633
GSE37065Down-0.0074389756
GSE28863_A1Down-0.0226418605
GSE28863_A2Up0.0521778674
GSE28863_A3Up0.3000404354
GSE28863_A4Up0.1014082691
GSE48662Up0.0190142002

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

23644601However, we did not find increased levels of markers of euchromatin or derepression of the 7q VIPR2 gene
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