HCSGD entry for VDAC1
1. General information
| Official gene symbol | VDAC1 |
|---|---|
| Entrez ID | 7416 |
| Gene full name | voltage-dependent anion channel 1 |
| Other gene symbols | PORIN VDAC-1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001662 | Behavioral fear response | IEA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005739 | Mitochondrion | TAS | cellular_component |
| GO:0005741 | Mitochondrial outer membrane | IEA | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006820 | Anion transport | TAS | biological_process |
| GO:0006915 | Apoptotic process | TAS | biological_process |
| GO:0007270 | Neuron-neuron synaptic transmission | IEA | biological_process |
| GO:0007612 | Learning | IEA | biological_process |
| GO:0008308 | Voltage-gated anion channel activity | IEA ISS TAS | molecular_function |
| GO:0015288 | Porin activity | IEA | molecular_function |
| GO:0016020 | Membrane | ISS | cellular_component |
| GO:0016032 | Viral process | IEA | biological_process |
| GO:0034220 | Ion transmembrane transport | ISS TAS | biological_process |
| GO:0034765 | Regulation of ion transmembrane transport | ISS TAS | biological_process |
| GO:0042645 | Mitochondrial nucleoid | IDA | cellular_component |
| GO:0046930 | Pore complex | TAS | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4768807834 | 0.2668323696 | 0.9999902473 | 0.9890025176 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2802155351 |
| GSE13712_SHEAR | Up | 0.1931597552 |
| GSE13712_STATIC | Up | 0.2300834828 |
| GSE19018 | Up | 0.3531314508 |
| GSE19899_A1 | Up | 0.1680050721 |
| GSE19899_A2 | Up | 0.1099902971 |
| PubMed_21979375_A1 | Up | 0.0811554857 |
| PubMed_21979375_A2 | Down | -0.1115995297 |
| GSE35957 | Down | -0.1668303977 |
| GSE36640 | Down | -0.0072872362 |
| GSE54402 | Up | 0.2030880696 |
| GSE9593 | Up | 0.1037900107 |
| GSE43922 | Down | -0.0370684400 |
| GSE24585 | Down | -0.5393438322 |
| GSE37065 | Down | -0.0971844026 |
| GSE28863_A1 | Up | 0.0834015651 |
| GSE28863_A2 | Down | -0.1575797128 |
| GSE28863_A3 | Up | 0.0406942683 |
| GSE28863_A4 | Up | 0.1268476918 |
| GSE48662 | Down | -0.4166298437 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Aluminium monostearate | DB01375 | - |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1301-3p | MIMAT0005797 | MIRT036008 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320c | MIMAT0005793 | MIRT036168 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-877-5p | MIMAT0004949 | MIRT037371 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037391 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039673 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044747 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT045947 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047728 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-197-3p | MIMAT0000227 | MIRT048149 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-106a-5p | MIMAT0000103 | MIRT048331 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
