HCSGD entry for UQCRC1

1. General information

Official gene symbolUQCRC1
Entrez ID7384
Gene full nameubiquinol-cytochrome c reductase core protein I
Other gene symbolsD3S3191 QCR1 UQCR1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005739MitochondrionIDAcellular_component
GO:0005743Mitochondrial inner membraneTAScellular_component
GO:0005746Mitochondrial respiratory chainTAScellular_component
GO:0005750Mitochondrial respiratory chain complex IIIIEAcellular_component
GO:0006119Oxidative phosphorylationTASbiological_process
GO:0006122Mitochondrial electron transport, ubiquinol to cytochrome cIEAbiological_process
GO:0006810TransportTASbiological_process
GO:0006812Cation transportTASbiological_process
GO:0008121Ubiquinol-cytochrome-c reductase activityTASmolecular_function
GO:0009060Aerobic respirationTASbiological_process
GO:0014823Response to activityIEAbiological_process
GO:0015672Monovalent inorganic cation transportTASbiological_process
GO:0022904Respiratory electron transport chainTASbiological_process
GO:0032403Protein complex bindingIEAmolecular_function
GO:0034220Ion transmembrane transportTASbiological_process
GO:0043279Response to alkaloidIEAbiological_process
GO:0044237Cellular metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0055085Transmembrane transportTASbiological_process
GO:0055114Oxidation-reduction processTASbiological_process
GO:1902600Hydrogen ion transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.82862510160.07817543410.99999024730.5289603085

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2368421768
GSE13712_SHEARDown-0.0939600573
GSE13712_STATICUp0.0111970269
GSE19018Up0.1446475818
GSE19899_A1Up0.0294012962
GSE19899_A2Up0.1583568622
PubMed_21979375_A1Down-1.1115166985
PubMed_21979375_A2Up0.5251584863
GSE35957Down-0.5966402166
GSE36640Down-0.4617491705
GSE54402Up0.1715697613
GSE9593Down-0.2243039622
GSE43922Up0.0008742166
GSE24585Down-0.1820602211
GSE37065Down-0.2861945621
GSE28863_A1Down-0.2679026228
GSE28863_A2Down-0.3370211988
GSE28863_A3Down-0.5163349752
GSE28863_A4Down-0.1957198419
GSE48662Up0.2053107634

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-TriolDB04141 EXPT00697
MyxothiazolDB04741 -
5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazoleDB04799 -
METHYL (2Z)-2-(2-{[6-(2-CYANOPHENOXY)PYRIMIDIN-4-YL]OXY}PHENYL)-3-METHOXYACRYLATEDB07401 -
(5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONEDB07763 -
FAMOXADONEDB07778 -
METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATEDB08330 -
2-NONYL-4-HYDROXYQUINOLINE N-OXIDEDB08453 -
UBIQUINONE-2DB08690 -

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1296-5pMIMAT0005794MIRT036152CLASHFunctional MTI (Weak)23622248
hsa-miR-320bMIMAT0005792MIRT036243CLASHFunctional MTI (Weak)23622248
hsa-miR-877-3pMIMAT0004950MIRT036834CLASHFunctional MTI (Weak)23622248
hsa-miR-183-5pMIMAT0000261MIRT047130CLASHFunctional MTI (Weak)23622248
hsa-miR-30c-5pMIMAT0000244MIRT048017CLASHFunctional MTI (Weak)23622248
hsa-miR-93-5pMIMAT0000093MIRT048908CLASHFunctional MTI (Weak)23622248
hsa-miR-20a-5pMIMAT0000075MIRT050603CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.