HCSGD entry for UPP1
1. General information
| Official gene symbol | UPP1 |
|---|---|
| Entrez ID | 7378 |
| Gene full name | uridine phosphorylase 1 |
| Other gene symbols | UDRPASE UP UPASE UPP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004850 | Uridine phosphorylase activity | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006139 | Nucleobase-containing compound metabolic process | TAS | biological_process |
| GO:0006206 | Pyrimidine nucleobase metabolic process | TAS | biological_process |
| GO:0006220 | Pyrimidine nucleotide metabolic process | IEA | biological_process |
| GO:0009116 | Nucleoside metabolic process | IEA | biological_process |
| GO:0009166 | Nucleotide catabolic process | IEA | biological_process |
| GO:0042149 | Cellular response to glucose starvation | IEA | biological_process |
| GO:0043097 | Pyrimidine nucleoside salvage | TAS | biological_process |
| GO:0044206 | UMP salvage | IEA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046108 | Uridine metabolic process | IEA | biological_process |
| GO:0046135 | Pyrimidine nucleoside catabolic process | TAS | biological_process |
| GO:0055086 | Nucleobase-containing small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0000873713 | 0.9090988868 | 0.0273773810 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 1.6225791449 |
| GSE13712_SHEAR | Up | 0.6737648604 |
| GSE13712_STATIC | Up | 0.4555983656 |
| GSE19018 | Down | -0.8827368329 |
| GSE19899_A1 | Up | 2.6743888645 |
| GSE19899_A2 | Up | 1.5302533027 |
| PubMed_21979375_A1 | Up | 5.9552522743 |
| PubMed_21979375_A2 | Up | 3.5345723649 |
| GSE35957 | Up | 0.1966916972 |
| GSE36640 | Up | 0.2902493134 |
| GSE54402 | Up | 2.6424261212 |
| GSE9593 | Up | 0.3665331270 |
| GSE43922 | Up | 1.6167762001 |
| GSE24585 | Down | -0.0841467816 |
| GSE37065 | Up | 0.1103469157 |
| GSE28863_A1 | Down | -0.4499265558 |
| GSE28863_A2 | Up | 0.7549538849 |
| GSE28863_A3 | Up | 0.0059051575 |
| GSE28863_A4 | Down | -0.0303483784 |
| GSE48662 | Up | 0.5257754074 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| RP101 | DB05041 | - |
| 1-((2-HYDROXYETHOXY)METHYL)-5-BENZYLPYRIMIDINE-2,4(1H,3H)-DIONE | DB07437 | - |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024540 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026152 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
