HCSGD entry for UGDH
1. General information
| Official gene symbol | UGDH |
|---|---|
| Entrez ID | 7358 |
| Gene full name | UDP-glucose 6-dehydrogenase |
| Other gene symbols | GDH UDP-GlcDH UDPGDH UGD |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001702 | Gastrulation with mouth forming second | IEA | biological_process |
| GO:0003979 | UDP-glucose 6-dehydrogenase activity | IEA TAS | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006011 | UDP-glucose metabolic process | TAS | biological_process |
| GO:0006024 | Glycosaminoglycan biosynthetic process | TAS | biological_process |
| GO:0006065 | UDP-glucuronate biosynthetic process | IEA TAS | biological_process |
| GO:0006805 | Xenobiotic metabolic process | TAS | biological_process |
| GO:0009055 | Electron carrier activity | TAS | molecular_function |
| GO:0016616 | Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | IEA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0051287 | NAD binding | IEA | molecular_function |
| GO:0052695 | Cellular glucuronidation | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8807759622 | 0.0195669807 | 0.9999902473 | 0.2729319025 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3576550666 |
| GSE13712_SHEAR | Down | -0.1677339868 |
| GSE13712_STATIC | Down | -0.1578421406 |
| GSE19018 | Down | -0.3417996670 |
| GSE19899_A1 | Down | -0.7317989354 |
| GSE19899_A2 | Down | -0.5433115417 |
| PubMed_21979375_A1 | Down | -0.9010082503 |
| PubMed_21979375_A2 | Down | -1.0457099839 |
| GSE35957 | Down | -0.5502409522 |
| GSE36640 | Down | -0.4431361371 |
| GSE54402 | Down | -0.0169547927 |
| GSE9593 | Down | -0.0256958560 |
| GSE43922 | Down | -0.2928903235 |
| GSE24585 | Up | 0.0805073829 |
| GSE37065 | Up | 0.2120843357 |
| GSE28863_A1 | Up | 0.3001137149 |
| GSE28863_A2 | Up | 0.6577334041 |
| GSE28863_A3 | Down | -0.0626706380 |
| GSE28863_A4 | Up | 0.2013591534 |
| GSE48662 | Down | -0.4295104896 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| NADH | DB00157 | NUTR00041 | DB01907 | EXPT02287 | DB03527 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT000913 | Microarray | Functional MTI (Weak) | 18362358 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT000913 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-15a-5p | MIMAT0000068 | MIRT000914 | Microarray | Functional MTI (Weak) | 18362358 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT016763 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020547 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-9-5p | MIMAT0000441 | MIRT021343 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028401 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028832 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-24-3p | MIMAT0000080 | MIRT030373 | Microarray | Functional MTI (Weak) | 19748357 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049509 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-15a-5p | MIMAT0000068 | NA | hsa-miR-15a | 18362358 | |||
| hsa-miR-16-5p | MIMAT0000069 | NA | hsa-miR-16 | 18362358 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
