HCSGD entry for UCP3

1. General information

Official gene symbolUCP3
Entrez ID7352
Gene full nameuncoupling protein 3 (mitochondrial, proton carrier)
Other gene symbolsSLC25A9
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000303Response to superoxideIEAbiological_process
GO:0001666Response to hypoxiaIEAbiological_process
GO:0005215Transporter activityTASmolecular_function
GO:0005739MitochondrionTAScellular_component
GO:0005743Mitochondrial inner membraneTAScellular_component
GO:0006629Lipid metabolic processTASbiological_process
GO:0006631Fatty acid metabolic processIEAbiological_process
GO:0006839Mitochondrial transportIEAbiological_process
GO:0007568AgingIEAbiological_process
GO:0007584Response to nutrientIEAbiological_process
GO:0007585Respiratory gaseous exchangeTASbiological_process
GO:0009409Response to coldIEAbiological_process
GO:0014823Response to activityIEAbiological_process
GO:0015992Proton transportTASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0017077Oxidative phosphorylation uncoupler activityIEAmolecular_function
GO:0022904Respiratory electron transport chainTASbiological_process
GO:0031966Mitochondrial membraneIEAcellular_component
GO:0032868Response to insulinIEAbiological_process
GO:0032870Cellular response to hormone stimulusIEAbiological_process
GO:0044237Cellular metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0051384Response to glucocorticoidIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.37092111620.68295622130.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1003415259
GSE13712_SHEARUp0.0224634588
GSE13712_STATICUp0.0463970927
GSE19018Down-0.0759166759
GSE19899_A1Up0.0216565937
GSE19899_A2Up0.0508004414
PubMed_21979375_A1Up0.0278384505
PubMed_21979375_A2Down-0.0045985213
GSE35957Up0.0513644010
GSE36640Down-0.1407901821
GSE54402Up0.0147115593
GSE9593Up0.0142535091
GSE43922Up0.0114439738
GSE24585Down-0.0811351667
GSE37065Up0.0648583000
GSE28863_A1Up0.1181225321
GSE28863_A2Down-0.1676258963
GSE28863_A3Down-0.0619009930
GSE28863_A4Up0.0360258161
GSE48662Up1.8304377726

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-342-5pMIMAT0004694MIRT038202CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.