HCSGD entry for UBP1


1. General information

Official gene symbolUBP1
Entrez ID7342
Gene full nameupstream binding protein 1 (LBP-1a)
Other gene symbolsLBP-1B LBP-1a LBP1A LBP1B
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001525AngiogenesisIEAbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityTASmolecular_function
GO:0003714Transcription corepressor activityTASmolecular_function
GO:0005634NucleusTAScellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006357Regulation of transcription from RNA polymerase II promoterTASbiological_process
GO:0019079Viral genome replicationTASbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.92599958970.16821096460.99999024730.7930220591

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1339939168
GSE13712_SHEARUp0.1251622192
GSE13712_STATICDown-0.1345984633
GSE19018Down-0.5476143704
GSE19899_A1Down-0.1269023413
GSE19899_A2Up0.2798405060
PubMed_21979375_A1Down-0.1590825314
PubMed_21979375_A2Up0.1260392607
GSE35957Down-0.1244981212
GSE36640Down-0.1664908727
GSE54402Up0.1179718730
GSE9593Down-0.7322919414
GSE43922Down-0.0324772728
GSE24585Up0.0153370577
GSE37065Up0.1638639940
GSE28863_A1Down-0.0466390739
GSE28863_A2Down-0.0796225481
GSE28863_A3Up0.0448231550
GSE28863_A4Up0.0726216236
GSE48662Down-0.2563548426

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-183-5pMIMAT0000261MIRT025006SequencingFunctional MTI (Weak)20371350
hsa-miR-34a-5pMIMAT0000255MIRT025583SequencingFunctional MTI (Weak)20371350
hsa-miR-182-5pMIMAT0000259MIRT047198CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.