HCSGD entry for UBE2H
1. General information
| Official gene symbol | UBE2H |
|---|---|
| Entrez ID | 7328 |
| Gene full name | ubiquitin-conjugating enzyme E2H |
| Other gene symbols | E2-20K GID3 UBC8 UBCH UBCH2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0006511 | Ubiquitin-dependent protein catabolic process | TAS | biological_process |
| GO:0016881 | Acid-amino acid ligase activity | IEA | molecular_function |
| GO:0070936 | Protein K48-linked ubiquitination | IDA | biological_process |
| GO:0070979 | Protein K11-linked ubiquitination | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0162354432 | 0.9745524220 | 0.3137664469 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0515407390 |
| GSE13712_SHEAR | Up | 0.2963310402 |
| GSE13712_STATIC | Up | 0.1877922478 |
| GSE19018 | Up | 0.6249345615 |
| GSE19899_A1 | Up | 0.0219038078 |
| GSE19899_A2 | Up | 0.5145500656 |
| PubMed_21979375_A1 | Up | 0.0354675035 |
| PubMed_21979375_A2 | Up | 0.5794422350 |
| GSE35957 | Up | 0.1088333033 |
| GSE36640 | Up | 1.0043500669 |
| GSE54402 | Down | -0.3176159511 |
| GSE9593 | Up | 0.5343839569 |
| GSE43922 | Down | -0.0370718797 |
| GSE24585 | Up | 0.6352722264 |
| GSE37065 | Up | 0.0282661721 |
| GSE28863_A1 | Up | 0.2441247694 |
| GSE28863_A2 | Up | 0.2358827890 |
| GSE28863_A3 | Up | 0.3091511167 |
| GSE28863_A4 | Down | -0.0175353670 |
| GSE48662 | Up | 0.3212552484 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-451a | MIMAT0001631 | MIRT016629 | Microarray | Functional MTI (Weak) | 20218812 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020674 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028404 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1915-5p | MIMAT0007891 | MIRT035770 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-501-3p | MIMAT0004774 | MIRT037987 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049032 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051591 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
