HCSGD entry for UBE2G1
1. General information
| Official gene symbol | UBE2G1 |
|---|---|
| Entrez ID | 7326 |
| Gene full name | ubiquitin-conjugating enzyme E2G 1 |
| Other gene symbols | E217K UBC7 UBE2G |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | IDA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0006511 | Ubiquitin-dependent protein catabolic process | TAS | biological_process |
| GO:0016881 | Acid-amino acid ligase activity | IEA | molecular_function |
| GO:0031625 | Ubiquitin protein ligase binding | IPI | molecular_function |
| GO:0070534 | Protein K63-linked ubiquitination | IDA | biological_process |
| GO:0070936 | Protein K48-linked ubiquitination | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4373922305 | 0.8650741195 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1712975584 |
| GSE13712_SHEAR | Up | 0.0475655673 |
| GSE13712_STATIC | Down | -0.0325638290 |
| GSE19018 | Up | 0.2402131826 |
| GSE19899_A1 | Up | 0.1177733240 |
| GSE19899_A2 | Up | 0.1366510865 |
| PubMed_21979375_A1 | Up | 0.2013509643 |
| PubMed_21979375_A2 | Up | 0.1948538717 |
| GSE35957 | Up | 0.0078638080 |
| GSE36640 | Down | -0.3710315048 |
| GSE54402 | Up | 0.0622301866 |
| GSE9593 | Up | 0.1353213460 |
| GSE43922 | Up | 0.1677283633 |
| GSE24585 | Up | 0.0294957771 |
| GSE37065 | Up | 0.0147553708 |
| GSE28863_A1 | Down | -0.0036371599 |
| GSE28863_A2 | Down | -0.1875290103 |
| GSE28863_A3 | Down | -0.3142613178 |
| GSE28863_A4 | Up | 0.1538908049 |
| GSE48662 | Down | -0.2446379592 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-18a-5p | MIMAT0000072 | MIRT031342 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-1226-3p | MIMAT0005577 | MIRT036424 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044475 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
