HCSGD entry for C8B
1. General information
| Official gene symbol | C8B |
|---|---|
| Entrez ID | 732 |
| Gene full name | complement component 8, beta polypeptide |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005579 | Membrane attack complex | IEA | cellular_component |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0006955 | Immune response | IEA TAS | biological_process |
| GO:0006956 | Complement activation | TAS | biological_process |
| GO:0006957 | Complement activation, alternative pathway | IEA | biological_process |
| GO:0006958 | Complement activation, classical pathway | IEA | biological_process |
| GO:0016020 | Membrane | TAS | cellular_component |
| GO:0019835 | Cytolysis | IEA | biological_process |
| GO:0030449 | Regulation of complement activation | TAS | biological_process |
| GO:0032403 | Protein complex binding | IEA | molecular_function |
| GO:0045087 | Innate immune response | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6886746704 | 0.8381449945 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0958309159 |
| GSE13712_SHEAR | Up | 0.0080400864 |
| GSE13712_STATIC | Down | -0.1387381206 |
| GSE19018 | Down | -0.0267362245 |
| GSE19899_A1 | Up | 0.1253487241 |
| GSE19899_A2 | Up | 0.1003621388 |
| PubMed_21979375_A1 | Up | 0.3701343888 |
| PubMed_21979375_A2 | Down | -0.1297416874 |
| GSE35957 | Up | 0.2120855119 |
| GSE36640 | Down | -0.0195403638 |
| GSE54402 | Down | -0.0436499681 |
| GSE9593 | Down | -0.1198656962 |
| GSE43922 | Up | 0.0147714108 |
| GSE24585 | Up | 0.0929070861 |
| GSE37065 | Down | -0.0005427331 |
| GSE28863_A1 | Down | -0.1188452874 |
| GSE28863_A2 | Up | 0.1671592222 |
| GSE28863_A3 | Up | 0.2416296111 |
| GSE28863_A4 | Up | 0.0530063741 |
| GSE48662 | Up | 0.0681701283 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
