HCSGD entry for TUFM
1. General information
| Official gene symbol | TUFM |
|---|---|
| Entrez ID | 7284 |
| Gene full name | Tu translation elongation factor, mitochondrial |
| Other gene symbols | COXPD4 EF-TuMT EFTU P43 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003746 | Translation elongation factor activity | IDA | molecular_function |
| GO:0003924 | GTPase activity | IEA | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0006414 | Translational elongation | IDA | biological_process |
| GO:0042645 | Mitochondrial nucleoid | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1215042969 | 0.7051120550 | 0.7128265479 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4175607828 |
| GSE13712_SHEAR | Down | -0.1251040970 |
| GSE13712_STATIC | Up | 0.0443333424 |
| GSE19018 | Up | 0.0085866791 |
| GSE19899_A1 | Up | 0.2239140855 |
| GSE19899_A2 | Up | 0.4674670199 |
| PubMed_21979375_A1 | Up | 0.6342364827 |
| PubMed_21979375_A2 | Up | 0.7277218043 |
| GSE35957 | Down | -0.2219685876 |
| GSE36640 | Up | 0.2633576107 |
| GSE54402 | Up | 0.0993243299 |
| GSE9593 | Down | -0.3236032176 |
| GSE43922 | Up | 0.5013350641 |
| GSE24585 | Down | -0.5612418829 |
| GSE37065 | Down | -0.3376924616 |
| GSE28863_A1 | Down | -0.0041357004 |
| GSE28863_A2 | Down | -0.0415836195 |
| GSE28863_A3 | Up | 0.0960912540 |
| GSE28863_A4 | Up | 0.2107913445 |
| GSE48662 | Down | -0.1109678734 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Guanosine-5'-Diphosphate | DB04315 | EXPT01573 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-615-3p | MIMAT0003283 | MIRT039619 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-339-5p | MIMAT0000764 | MIRT042804 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-5p | MIMAT0000761 | MIRT043186 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045200 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049214 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-28-5p | MIMAT0000085 | MIRT050010 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-1260b | MIMAT0015041 | MIRT052711 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
