HCSGD entry for TUBB2A
1. General information
| Official gene symbol | TUBB2A |
|---|---|
| Entrez ID | 7280 |
| Gene full name | tubulin, beta 2A class IIa |
| Other gene symbols | TUBB TUBB2 dJ40E16.7 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003924 | GTPase activity | IEA | molecular_function |
| GO:0005200 | Structural constituent of cytoskeleton | IEA | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005874 | Microtubule | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006457 | Protein folding | TAS | biological_process |
| GO:0007017 | Microtubule-based process | IEA | biological_process |
| GO:0015630 | Microtubule cytoskeleton | IDA | cellular_component |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0051084 | 'de novo' posttranslational protein folding | TAS | biological_process |
| GO:0051258 | Protein polymerization | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7015121880 | 0.2750286083 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1753006893 |
| GSE13712_SHEAR | Down | -0.0109287589 |
| GSE13712_STATIC | Down | -0.0078023054 |
| GSE19018 | Up | 0.1047472212 |
| GSE19899_A1 | Up | 0.0594048354 |
| GSE19899_A2 | Up | 0.3227186329 |
| PubMed_21979375_A1 | Down | -0.1476562477 |
| PubMed_21979375_A2 | Up | 0.0917242698 |
| GSE35957 | Down | -0.5008249985 |
| GSE36640 | Up | 0.3191264102 |
| GSE54402 | Down | -0.1572182045 |
| GSE9593 | Down | -0.1308068573 |
| GSE43922 | Down | -0.1067715248 |
| GSE24585 | Up | 0.0514390093 |
| GSE37065 | Down | -0.4982979975 |
| GSE28863_A1 | Down | -0.2392737061 |
| GSE28863_A2 | Up | 0.2559244726 |
| GSE28863_A3 | Up | 0.0691974242 |
| GSE28863_A4 | Down | -0.2508997464 |
| GSE48662 | Down | -0.1282210384 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| CYT997 | DB05147 | - |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-484 | MIMAT0002174 | MIRT041626 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
