HCSGD entry for TTPA
1. General information
| Official gene symbol | TTPA |
|---|---|
| Entrez ID | 7274 |
| Gene full name | tocopherol (alpha) transfer protein |
| Other gene symbols | ATTP AVED TTP1 alphaTTP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001892 | Embryonic placenta development | IEA | biological_process |
| GO:0005215 | Transporter activity | IEA | molecular_function |
| GO:0005546 | Phosphatidylinositol-4,5-bisphosphate binding | ISS | molecular_function |
| GO:0005770 | Late endosome | IEA | cellular_component |
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0006629 | Lipid metabolic process | TAS | biological_process |
| GO:0006810 | Transport | TAS | biological_process |
| GO:0007584 | Response to nutrient | IEA | biological_process |
| GO:0008431 | Vitamin E binding | ISS | molecular_function |
| GO:0009268 | Response to pH | IEA | biological_process |
| GO:0009636 | Response to toxic substance | IEA | biological_process |
| GO:0042360 | Vitamin E metabolic process | IEA | biological_process |
| GO:0043325 | Phosphatidylinositol-3,4-bisphosphate binding | ISS | molecular_function |
| GO:0046909 | Intermembrane transport | ISS | biological_process |
| GO:0051180 | Vitamin transport | ISS | biological_process |
| GO:0051452 | Intracellular pH reduction | IEA | biological_process |
| GO:0060548 | Negative regulation of cell death | IEA | biological_process |
| GO:0090212 | Negative regulation of establishment of blood-brain barrier | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8080292922 | 0.6516642567 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0263704137 |
| GSE13712_SHEAR | Up | 0.1189662903 |
| GSE13712_STATIC | Down | -0.0453182004 |
| GSE19018 | Up | 0.0569313584 |
| GSE19899_A1 | Down | 0.0000000000 |
| GSE19899_A2 | Up | 0.0506724141 |
| PubMed_21979375_A1 | Up | 0.2004538991 |
| PubMed_21979375_A2 | Up | 0.0029397697 |
| GSE35957 | Up | 0.0554768208 |
| GSE36640 | Down | -0.0079642750 |
| GSE54402 | Up | 0.1428715186 |
| GSE9593 | Down | -0.1830430349 |
| GSE43922 | Up | 0.0163064035 |
| GSE24585 | Up | 0.1951844381 |
| GSE37065 | Down | -0.0340184720 |
| GSE28863_A1 | Down | -0.2835667554 |
| GSE28863_A2 | Down | -0.2950219935 |
| GSE28863_A3 | Up | 0.1052058794 |
| GSE28863_A4 | Up | 0.0122318112 |
| GSE48662 | Up | 0.0912750041 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024457 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026314 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
