HCSGD entry for TTC1
1. General information
| Official gene symbol | TTC1 |
|---|---|
| Entrez ID | 7265 |
| Gene full name | tetratricopeptide repeat domain 1 |
| Other gene symbols | TPR1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005778 | Peroxisomal membrane | IDA | cellular_component |
| GO:0006457 | Protein folding | NAS | biological_process |
| GO:0051082 | Unfolded protein binding | NAS | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0708288325 | 0.9213079860 | 0.5682966504 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.6412715387 |
| GSE13712_SHEAR | Down | -0.4035558400 |
| GSE13712_STATIC | Up | 0.0155226937 |
| GSE19018 | Down | -0.1911307086 |
| GSE19899_A1 | Up | 0.3845414979 |
| GSE19899_A2 | Up | 0.1262306846 |
| PubMed_21979375_A1 | Up | 0.6869121008 |
| PubMed_21979375_A2 | Up | 0.3951423003 |
| GSE35957 | Up | 0.0140581133 |
| GSE36640 | Up | 0.4447178595 |
| GSE54402 | Up | 0.0614926963 |
| GSE9593 | Up | 0.1528493455 |
| GSE43922 | Up | 0.1191469372 |
| GSE24585 | Down | -0.2332926199 |
| GSE37065 | Up | 0.1543546357 |
| GSE28863_A1 | Up | 0.0816188007 |
| GSE28863_A2 | Up | 0.2681253364 |
| GSE28863_A3 | Up | 0.3394044827 |
| GSE28863_A4 | Down | -0.1988624029 |
| GSE48662 | Down | -0.0590028131 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT031698 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-15b-5p | MIMAT0000417 | MIRT046424 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-15a-5p | MIMAT0000068 | MIRT051350 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
