HCSGD entry for TSN
1. General information
| Official gene symbol | TSN |
|---|---|
| Entrez ID | 7247 |
| Gene full name | translin |
| Other gene symbols | BCLF-1 C3PO RCHF1 REHF-1 TBRBP TRSLN |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | TAS | molecular_function |
| GO:0003729 | MRNA binding | IEA | molecular_function |
| GO:0004519 | Endonuclease activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006310 | DNA recombination | TAS | biological_process |
| GO:0032403 | Protein complex binding | IEA | molecular_function |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9538086471 | 0.0478087497 | 0.9999902473 | 0.4095152945 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5058414608 |
| GSE13712_SHEAR | Down | -0.1950096467 |
| GSE13712_STATIC | Down | -0.2394927693 |
| GSE19018 | Down | -0.2545542082 |
| GSE19899_A1 | Down | -0.3368967622 |
| GSE19899_A2 | Down | -0.3475016241 |
| PubMed_21979375_A1 | Up | 0.3542386943 |
| PubMed_21979375_A2 | Down | -0.3630139020 |
| GSE35957 | Up | 0.1097028121 |
| GSE36640 | Down | -0.5584922215 |
| GSE54402 | Down | -0.0502689443 |
| GSE9593 | Up | 0.1054889680 |
| GSE43922 | Down | -0.0194242339 |
| GSE24585 | Down | -0.2309213872 |
| GSE37065 | Down | -0.1706735700 |
| GSE28863_A1 | Down | -0.1006584201 |
| GSE28863_A2 | Up | 0.2559921832 |
| GSE28863_A3 | Down | -0.2997337844 |
| GSE28863_A4 | Down | -0.2715586658 |
| GSE48662 | Down | -0.5823915130 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022293 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025313 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025673 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT027952 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-221-3p | MIMAT0000278 | MIRT046853 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
