HCSGD entry for TRPC3
1. General information
| Official gene symbol | TRPC3 |
|---|---|
| Entrez ID | 7222 |
| Gene full name | transient receptor potential cation channel, subfamily C, member 3 |
| Other gene symbols | TRP3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005262 | Calcium channel activity | IEA TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | IDA | cellular_component |
| GO:0006816 | Calcium ion transport | TAS | biological_process |
| GO:0007411 | Axon guidance | TAS | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0007602 | Phototransduction | TAS | biological_process |
| GO:0010524 | Positive regulation of calcium ion transport into cytosol | IDA | biological_process |
| GO:0015279 | Store-operated calcium channel activity | TAS | molecular_function |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030168 | Platelet activation | TAS | biological_process |
| GO:0033198 | Response to ATP | IDA | biological_process |
| GO:0051592 | Response to calcium ion | IDA | biological_process |
| GO:0070588 | Calcium ion transmembrane transport | IDA | biological_process |
| GO:0070679 | Inositol 1,4,5 trisphosphate binding | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9248828654 | 0.0139703469 | 0.9999902473 | 0.2324936829 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0077287423 |
| GSE13712_SHEAR | Up | 0.1122754685 |
| GSE13712_STATIC | Up | 0.0668962369 |
| GSE19018 | Down | -0.6585370645 |
| GSE19899_A1 | Down | -0.1354143567 |
| GSE19899_A2 | Down | -1.2086077439 |
| PubMed_21979375_A1 | Down | -1.0191346266 |
| PubMed_21979375_A2 | Down | -0.4474888389 |
| GSE35957 | Up | 0.2710142551 |
| GSE36640 | Down | -2.4473422055 |
| GSE54402 | Down | -1.3529941995 |
| GSE9593 | Up | 0.0346866685 |
| GSE43922 | Down | -0.1560521693 |
| GSE24585 | Up | 0.3731939517 |
| GSE37065 | Down | -0.0005482976 |
| GSE28863_A1 | Up | 0.6127474230 |
| GSE28863_A2 | Down | -0.2167936391 |
| GSE28863_A3 | Down | -0.0293554870 |
| GSE28863_A4 | Down | -0.1772972068 |
| GSE48662 | Down | -0.4017057474 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020161 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-221-3p | MIMAT0000278 | MIRT024166 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-196a-5p | MIMAT0000226 | MIRT026076 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031132 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
