HCSGD entry for ACTG2
1. General information
| Official gene symbol | ACTG2 |
|---|---|
| Entrez ID | 72 |
| Gene full name | actin, gamma 2, smooth muscle, enteric |
| Other gene symbols | ACT ACTA3 ACTE ACTL3 ACTSG |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005856 | Cytoskeleton | IEA | cellular_component |
| GO:0006936 | Muscle contraction | TAS | biological_process |
| GO:0071944 | Cell periphery | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9452990350 | 0.0063154022 | 0.9999902473 | 0.1617048591 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1748285820 |
| GSE13712_SHEAR | Up | 0.1876265784 |
| GSE13712_STATIC | Up | 0.0628237938 |
| GSE19018 | Down | -0.5242053777 |
| GSE19899_A1 | Down | -1.1850047666 |
| GSE19899_A2 | Down | -1.3700705444 |
| PubMed_21979375_A1 | Down | -2.1217461099 |
| PubMed_21979375_A2 | Down | -1.8200816200 |
| GSE35957 | Up | 0.3781105143 |
| GSE36640 | Up | 0.1731671153 |
| GSE54402 | Down | -0.5120388884 |
| GSE9593 | Down | -0.3505430040 |
| GSE43922 | Down | -1.2484317594 |
| GSE24585 | Up | 0.2469441508 |
| GSE37065 | Down | -0.3565996827 |
| GSE28863_A1 | Down | -0.0854545735 |
| GSE28863_A2 | Down | -0.0150033257 |
| GSE28863_A3 | Up | 0.1236886374 |
| GSE28863_A4 | Down | -0.1132895255 |
| GSE48662 | Down | -0.1958129817 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 15610763 | Genes specifically up-regulated by transdifferentiation but not by cellular senescence of PrSCs were metalloproteinase 1 tissue inhibitor (Timp1), transgelin (Tagln), gamma 2 actin (Actg2), plasminogen activator inhibitor 1 (Serpinel), insulin-like growth factor binding protein 3 (Igfbp3), parathyroid hormone-like hormone (Pthlp), Tgfb-1, four and a half LIM domains 2 (Fhl-2), hydrogen peroxide-inducible clone 5 (Hic5) and cartilage oligomeric matrix protein (Comp) |
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