HCSGD entry for TPMT
1. General information
| Official gene symbol | TPMT |
|---|---|
| Entrez ID | 7172 |
| Gene full name | thiopurine S-methyltransferase |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006139 | Nucleobase-containing compound metabolic process | TAS | biological_process |
| GO:0006805 | Xenobiotic metabolic process | TAS | biological_process |
| GO:0008119 | Thiopurine S-methyltransferase activity | IEA | molecular_function |
| GO:0032259 | Methylation | TAS | biological_process |
| GO:0033574 | Response to testosterone | IEA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9013135329 | 0.1267604954 | 0.9999902473 | 0.6852593551 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1420284041 |
| GSE13712_SHEAR | Down | -0.0829526740 |
| GSE13712_STATIC | Up | 0.1204100903 |
| GSE19018 | Down | -0.1434000705 |
| GSE19899_A1 | Down | -0.1157359978 |
| GSE19899_A2 | Down | -0.1487237555 |
| PubMed_21979375_A1 | Down | -0.3486340562 |
| PubMed_21979375_A2 | Down | -0.6845520982 |
| GSE35957 | Down | -0.0909415288 |
| GSE36640 | Down | -0.2859078412 |
| GSE54402 | Up | 0.1784966275 |
| GSE9593 | Up | 0.2261013029 |
| GSE43922 | Down | -0.5419542754 |
| GSE24585 | Up | 0.1882117879 |
| GSE37065 | Up | 0.1078506443 |
| GSE28863_A1 | Down | -0.3542675950 |
| GSE28863_A2 | Up | 0.0014475775 |
| GSE28863_A3 | Down | -0.1809137076 |
| GSE28863_A4 | Down | -0.0549020762 |
| GSE48662 | Down | -0.0352193301 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Olsalazine | DB01250 | - |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
