HCSGD entry for TNNT1
1. General information
| Official gene symbol | TNNT1 |
|---|---|
| Entrez ID | 7138 |
| Gene full name | troponin T type 1 (skeletal, slow) |
| Other gene symbols | ANM NEM5 STNT TNT TNTS |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003009 | Skeletal muscle contraction | IMP | biological_process |
| GO:0005523 | Tropomyosin binding | IMP | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005861 | Troponin complex | IDA IEA IMP | cellular_component |
| GO:0006937 | Regulation of muscle contraction | IEA | biological_process |
| GO:0030049 | Muscle filament sliding | TAS | biological_process |
| GO:0031014 | Troponin T binding | IEA | molecular_function |
| GO:0031444 | Slow-twitch skeletal muscle fiber contraction | IEA | biological_process |
| GO:0045932 | Negative regulation of muscle contraction | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6703595836 | 0.6869406368 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0118743250 |
| GSE13712_SHEAR | Down | -0.5258021821 |
| GSE13712_STATIC | Down | -0.1329682853 |
| GSE19018 | Up | 0.0049580230 |
| GSE19899_A1 | Down | -0.0213955691 |
| GSE19899_A2 | Up | 0.0264329222 |
| PubMed_21979375_A1 | Down | -0.3813517117 |
| PubMed_21979375_A2 | Down | -0.0006129410 |
| GSE35957 | Down | -0.1411043234 |
| GSE36640 | Up | 0.3574408435 |
| GSE54402 | Up | 0.3848461582 |
| GSE9593 | Up | 0.0095941830 |
| GSE43922 | Up | 0.0517321357 |
| GSE24585 | Up | 0.1788825170 |
| GSE37065 | Down | -0.1146821870 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.0972190171 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
