HCSGD entry for TLL2


1. General information

Official gene symbolTLL2
Entrez ID7093
Gene full nametolloid-like 2
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004222Metalloendopeptidase activityIEAmolecular_function
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0006508ProteolysisIEAbiological_process
GO:0007275Multicellular organismal developmentIEAbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0030154Cell differentiationIEAbiological_process
GO:0030198Extracellular matrix organizationTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.41645042740.94455587930.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1097423378
GSE13712_SHEARDown-0.1387689865
GSE13712_STATICUp0.1104755876
GSE19018Up0.0408750041
GSE19899_A1Up0.0400106345
GSE19899_A2Up0.1677522242
PubMed_21979375_A1Up0.2941086390
PubMed_21979375_A2Up0.1440781158
GSE35957Up0.0967352148
GSE36640Up0.2216915560
GSE54402Up0.0173724061
GSE9593Up0.4420474457
GSE43922Up0.0244026174
GSE24585Up0.0594715834
GSE37065Down-0.1569722603
GSE28863_A1Down-0.1535400155
GSE28863_A2Up0.0783604469
GSE28863_A3Up0.1839855423
GSE28863_A4Up0.0838460462
GSE48662Down-0.0611373980

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Carbobenzoxy-Pro-Lys-Phe-Y(Po2)-Ala-Pro-OmeDB01989 EXPT02604

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.