HCSGD entry for C1QBP

1. General information

Official gene symbolC1QBP
Entrez ID708
Gene full namecomplement component 1, q subcomponent binding protein
Other gene symbolsGC1QBP HABP1 SF2p32 gC1Q-R gC1qR p32
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0001849Complement component C1q bindingIDA IEAmolecular_function
GO:0003714Transcription corepressor activityIDAmolecular_function
GO:0003729MRNA bindingISSmolecular_function
GO:0005080Protein kinase C bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005540Hyaluronic acid bindingIDAmolecular_function
GO:0005615Extracellular spaceIEAcellular_component
GO:0005634NucleusIDA IEAcellular_component
GO:0005730NucleolusIEAcellular_component
GO:0005737CytoplasmISScellular_component
GO:0005739MitochondrionIDAcellular_component
GO:0005759Mitochondrial matrixIEAcellular_component
GO:0005829CytosolIDAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006397MRNA processingIEAbiological_process
GO:0006915Apoptotic processIEAbiological_process
GO:0006955Immune responseTASbiological_process
GO:0006958Complement activation, classical pathwayIEAbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0007597Blood coagulation, intrinsic pathwayTASbiological_process
GO:0008134Transcription factor bindingIDAmolecular_function
GO:0008380RNA splicingIEAbiological_process
GO:0009986Cell surfaceIDAcellular_component
GO:0014065Phosphatidylinositol 3-kinase signalingIMPbiological_process
GO:0016020MembraneIDAcellular_component
GO:0016032Viral processIEAbiological_process
GO:0030449Regulation of complement activationIDAbiological_process
GO:0030984Kininogen bindingIDAmolecular_function
GO:0031690Adrenergic receptor bindingIEA ISSmolecular_function
GO:0032689Negative regulation of interferon-gamma productionIDAbiological_process
GO:0032695Negative regulation of interleukin-12 productionIDAbiological_process
GO:0039534Negative regulation of MDA-5 signaling pathwayIDAbiological_process
GO:0039536Negative regulation of RIG-I signaling pathwayIDAbiological_process
GO:0042256Mature ribosome assemblyIMPbiological_process
GO:0043065Positive regulation of apoptotic processIMPbiological_process
GO:0045087Innate immune responseIEAbiological_process
GO:0045785Positive regulation of cell adhesionIMPbiological_process
GO:0048025Negative regulation of mRNA splicing, via spliceosomeIDAbiological_process
GO:0050687Negative regulation of defense response to virusIMPbiological_process
GO:0051897Positive regulation of protein kinase B signalingIMPbiological_process
GO:0070131Positive regulation of mitochondrial translationISSbiological_process
GO:0090023Positive regulation of neutrophil chemotaxisIDAbiological_process
GO:0097177Mitochondrial ribosome bindingISSmolecular_function
GO:1900026Positive regulation of substrate adhesion-dependent cell spreadingIMPbiological_process
GO:1901165Positive regulation of trophoblast cell migrationIMPbiological_process
GO:2000510Positive regulation of dendritic cell chemotaxisIMPbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.18615986470.11036862580.84182919460.6362678118

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.4171238257
GSE13712_SHEARUp0.3763505135
GSE13712_STATICUp0.3320053136
GSE19018Down-0.8361772827
GSE19899_A1Up0.2339930779
GSE19899_A2Up0.1839215551
PubMed_21979375_A1Up0.5667316979
PubMed_21979375_A2Up0.1302015067
GSE35957Down-0.2916931222
GSE36640Down-0.5508224597
GSE54402Up0.3531918017
GSE9593Down-0.4358483450
GSE43922Up0.2128328509
GSE24585Down-0.9169859117
GSE37065Down-0.2571126799
GSE28863_A1Up0.0710038457
GSE28863_A2Down-0.2890473969
GSE28863_A3Down-0.2105936346
GSE28863_A4Up0.3236807120
GSE48662Down-0.5131704899

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Hyaluronic acidDB08818 -

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-375MIMAT0000728MIRT001752MicroarrayFunctional MTI (Weak)20215506
hsa-miR-375MIMAT0000728MIRT001752Reporter assayFunctional MTI15806104
hsa-miR-93-3pMIMAT0004509MIRT038789CLASHFunctional MTI (Weak)23622248
hsa-miR-484MIMAT0002174MIRT041959CLASHFunctional MTI (Weak)23622248
hsa-miR-378a-5pMIMAT0000731MIRT043977CLASHFunctional MTI (Weak)23622248
hsa-miR-301a-3pMIMAT0000688MIRT044216CLASHFunctional MTI (Weak)23622248
hsa-miR-30b-5pMIMAT0000420MIRT046146CLASHFunctional MTI (Weak)23622248
hsa-miR-30c-5pMIMAT0000244MIRT048001CLASHFunctional MTI (Weak)23622248
hsa-miR-30a-3pMIMAT0000088MIRT049921CLASHFunctional MTI (Weak)23622248
Entries Per Page
Displaying Page of
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.