HCSGD entry for TIMP4


1. General information

Official gene symbolTIMP4
Entrez ID7079
Gene full nameTIMP metallopeptidase inhibitor 4
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005615Extracellular spaceIEAcellular_component
GO:0007417Central nervous system developmentIEAbiological_process
GO:0008150Biological_processNDbiological_process
GO:0008191Metalloendopeptidase inhibitor activityNASmolecular_function
GO:0010951Negative regulation of endopeptidase activityNASbiological_process
GO:0030017SarcomereIEAcellular_component
GO:0032496Response to lipopolysaccharideIEAbiological_process
GO:0034097Response to cytokineIEAbiological_process
GO:0042493Response to drugIEAbiological_process
GO:0042698Ovulation cycleIEAbiological_process
GO:0043434Response to peptide hormoneIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0052548Regulation of endopeptidase activityNASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.55428698380.13672417840.99999024730.7124761631

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1713066894
GSE13712_SHEARUp0.5141714266
GSE13712_STATICUp0.0628253984
GSE19018Down-0.0116698075
GSE19899_A1Down-0.0210198275
GSE19899_A2Down-0.0454437844
PubMed_21979375_A1Up0.0725070986
PubMed_21979375_A2Down-0.2630826954
GSE35957Down-0.2380660765
GSE36640Down-1.1699667887
GSE54402Down-0.6555208905
GSE9593Up0.2379214833
GSE43922Down-0.0624173841
GSE24585Up0.0016422702
GSE37065Down-0.1059181603
GSE28863_A1Up0.0241519513
GSE28863_A2Down-0.3300841006
GSE28863_A3Up0.4796978775
GSE28863_A4Down-0.0398070720
GSE48662Up0.1492205790

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.